766545-20-4

Basic information

• Product Name: 2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE HYDROCHLORIDE
• Synonyms: 2-chloro-5;6-naphthyridine hydrochloride;8-tetrahydro-1;2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE HCL;2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-PHTHYRIDINE HYDROCHLORIDE;1,6-Naphthyridine, 2-chloro-5,6,7,8-tetrahydro-, hydrochloride
• CAS NO: 766545-20-4
• Molecular Formula: C₈H₉ClN₂*ClH
• Molecular Weight: 168.62
• Product Categories: Heterocycle-Pyridine series
• Mol File: 766545-20-4.mol

Chemical Properties

• Boiling Point: 284.822 °C at 760 mmHg
• Flash Point: 126.056 °C
• Appearance: /
• Density: 1.227 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE HYDROCHLORIDE(766545-20-4)
• EPA Substance Registry System: 2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE HYDROCHLORIDE(766545-20-4)

Safety Data

• Hazardous Substances Data: 766545-20-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE HYDROCHLORIDE is used as a key intermediate in the synthesis of various pharmaceutical drugs for its potential to modulate specific biological pathways and interactions. Its unique structure allows for the design of drugs that can target diseases at the molecular level, offering new therapeutic options.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE HYDROCHLORIDE serves as a valuable compound for research purposes. Its properties and reactivity enable scientists to explore its potential in the development of new drugs and therapeutic agents, contributing to the advancement of medical treatments.
Further research and testing are essential to fully understand the potential uses and effects of 2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE HYDROCHLORIDE, ensuring its safe and effective application in the pharmaceutical industry.

InChI:InChI=1S/C8H9ClN2.ClH/c9-8-2-1-6-5-10-4-3-7(6)11-8;/h1-2,10H,3-5H2;1H

Upstream product

• 601514-58-3 6-benzyl-5,6,7,8-tetrahydro-[1,6]-naphthyridin-2(1H)-one 
• 23616-29-7 1,6-naphthyridin-2(1H)-one 
• 210539-04-1 6-benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 50893-53-3 carbonochloridic acid 1-chloro-ethyl ester 

Downstream Products

• 1151665-15-4 2-chloro-7,8-dihydro-5H-[1,6]naphthyridine-6-carboxylic acid tert-butyl ester 
• 1149333-40-3 2-amino-7,8-dihydro-1,6-naphthyridin-6(5H)-carboxylic acid tert-butyl ester 
• 1401034-46-5 tert-butyl 2-((9-((1r,4r)-4-methylcyclohexyl)-9H-pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate 
• 1412895-86-3 C₃₂H₄₅N₇OSi 
• 1401034-13-6 (S)-2-hydroxy-1-[2-({9-[(1r,4r)-4-methylcyclohexyl]-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl}amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]propan-1-one 
• 1401033-91-7 N-[6-(2-methoxyethyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]-9-[(1r,4r)-4-methylcyclohexyl]-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-amine 
• 1401033-90-6 N-[6-(2-fluoroethyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]-9-[(1r,4r)-4-methylcyclohexyl]-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-amine 
• 1401033-88-2 9-[(1r,4r)-4-methylcyclohexyl]-N-[6-(3,3,3-trifluoropropyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-amine 
• 1401034-48-7 methyl 2-{[6-(2-methoxy-2-oxoacetyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]{9-[(1r,4r)-4-methylcyclohexyl]-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl}amino}-2-oxoacetate 
• 1401033-87-1 2-[2-({9-[(1r,4r)-4-methylcyclohexyl]-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl}amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]-2-oxoacetic acid 
• 1401034-19-2 2-hydroxy-1-(2-((9-((1R,4R)-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethanone hydrochloride 
• 1401033-86-0 2-hydroxy-1-(2-((9-((1r,4r)-4-methylcyclohexyl)-9H-pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethanone 
• 1401034-47-6 2-(2-((9-((1r,4r)-4-methylcyclohexyl)-9H-pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)-2-oxoethyl acetate 

Relevant articles and documents

Compounds and methods of use

Compounds are provided according to Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein X1, X2, X3, X4, Y, A, L1, L2, R1, R2, R5, m and n are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.

ANTI-PULMONARY TUBERCULOSIS NITROIMIDAZOLE DERIVATIVE

Disclosed is a substituted nitroimidazole derivative, which is mainly used for treating related diseases caused by mycobacterial infections, such as Mycobacterium tuberculosis, especially being suitable for diseases caused by resistant Mycobacterium tuberculosis.

Substituted amide compound and application

The invention belongs to the field of agricultural bactericidal, insecticidal and acaricidal agents, and relates to a substituted amide compound and an application. The substituted amide compound has a structure as shown in a general formula I in the specification; and in the general formula I, substituents are defined in the specification. The compound provided by the invention has broad-spectrum bactericidal, insecticidal and acaricidal activities, has excellent control effects on diseases like cucumber downy mildew, corn rust, wheat powdery mildew and rice blast, especially has better control effects on the corn rust, also has excellent control effects on aphids and Tetranychus cinnabarinus, and especially can obtain good effects on the Tetranychus cinnabarinus at a low dosage.

Substituted tetrahydroisoquinoline compound and application

The invention discloses a substituted tetrahydroisoquinoline compound and application. The compound has a structure as shown in a general formula I in the specification; and in the general formula I, substituents are defined in the specification. The comp