768-36-5 Usage
Description
3-Pyrazinecarboxamide 1-oxide is a chemical compound that belongs to the class of pyrazines, which are aromatic and heterocyclic compounds. It is characterized by its structure containing two nitrogen and four carbon atoms. This specific compound is commonly utilized in medical and scientific research, although its detailed applications and properties are not extensively documented. As with any chemical substance, it is crucial to handle 3-Pyrazinecarboxamide 1-oxide with care and adhere to all safety protocols.
Uses
Used in Medical and Scientific Research:
3-Pyrazinecarboxamide 1-oxide is used as a research compound for its potential applications in various medical and scientific fields. Its unique structure and properties make it a valuable tool for studying different biological processes and developing new therapeutic approaches.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 3-Pyrazinecarboxamide 1-oxide may be used as a starting material or intermediate in the synthesis of various drug candidates. Its chemical properties and reactivity can be leveraged to create new compounds with potential therapeutic effects.
Used in Chemical Synthesis:
3-Pyrazinecarboxamide 1-oxide can also be employed in the synthesis of other organic compounds, such as dyes, pigments, and specialty chemicals. Its versatility in chemical reactions allows for the creation of a wide range of products with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 768-36-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,6 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 768-36:
(5*7)+(4*6)+(3*8)+(2*3)+(1*6)=95
95 % 10 = 5
So 768-36-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H5N3O2/c6-5(9)4-3-8(10)2-1-7-4/h1-3H,(H2,6,9)
768-36-5Relevant articles and documents
SUBSTITUTED PYRAZ INYLMETHYL SULFONAMIDES FOR USE AS. FUNGICIDES
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Page/Page column 55, (2009/10/22)
The present invention relates to the use of pyrazinylmethyl sulfonamides of formula (I) wherein Ra, n, R1, R2, R3, A, Y and D are as defined in the claims, and the N-oxides, and salts thereof for combating harmf
Metal-mediated inhibition of escherichia coli methionine aminopeptidase: Structure-activity relationships and development of a novel scoring function for metal-ligand interactions
Schiffmann, Rolf,Neugebauer, Alexander,Klein, Christian D.
, p. 511 - 522 (2007/10/03)
We report the discovery of thiabendazole as a potent inhibitor (K 1 = 0.4 μM) of Escherichia coli methionine aminopeptidase (ecMetAP) and the synthesis and pharmacological evaluation of thiabendazole congeners with activity in the upper nanomolar range, Elucidation of the X-ray structure of ecMetAP in complex with thiabendazole and an unrelated inhibitor that was independently described by another group showed that that both compounds bind to an additional CoII ion at the entrance of the active site. This unexpected finding explains the inactivity of the compounds under in vivo conditions. It also allows us to discuss the structure-activity relationships of this series of compounds in a meaningful way, based upon docking runs with an auxiliary metal ion, We describe a new scoring function for the evaluation of metal-mediated inhibitor binding that, unlike the previously used scoring function implemented in the docking program, allows us to distinguish between active and inactive compounds, Finally, conclusions for the structure-based design of in vivo-active inhibitors of ecMetAP are drawn.
Synthesis of 2-(D-Arabino-tetrahydroxybutyl)pyrazine-5-sulfonic acid
Fujii,Takagi,Seki
, p. 2169 - 2172 (2007/10/02)
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