76886-74-3

Upstream product

• 74879-25-7 -3,4-methylenedioxybenzaldehyde dimethyl acetal 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 120-57-0 piperonal 
• 74879-22-4 6-bromobenzo-1,3-dioxole-5-carboxaldehyde dimethyl acetal 
• 762-42-5 dimethyl acetylenedicarboxylate 

Downstream Products

• 75101-87-0 dimethyl 1,4-epoxy-1,2,3,4-tetrahydro-6,7-(methylenedioxy)-1-(1,2-cis)-(3',4',5'-trimethoxyphenyl)-2,3-cis-naphthalenedicarboxylate 
• 477-51-0 rac-(7'β,8α,8'percentb)-3',4',5'-trimethoxy-4,5-methylenedioxy-2,7'-cyclolignan-9',9-olide 
• 477-51-0 (5S,5aS,8aR)-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3′,4’:6,7]naphtho[2,3-d][1,3]-dioxol-6(5aH)-one 
• 75110-99-5 C₂₃H₂₄O₉ 
• 1643-12-5 (5S,6R,7R)-7-Hydroxymethyl-5-(3,4,5-trimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid methyl ester 
• 1643-12-5 (5S,6S,7S)-7-Hydroxymethyl-5-(3,4,5-trimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid methyl ester 
• 75101-88-1 C₂₃H₂₄O₉ 
• 75101-87-0 C₂₄H₂₄O₁₀ 
• 477-51-0 (+/-)-Isopicrodesoxypodophyllotoxin 
• 75101-87-0 dimethyl 1,4-epoxy-1,2,3,4-tetrahydro-6,7-(methylenedioxy)-1-(1,2-cis)-(3',4',5'-trimethoxyphenyl)-2,3-trans-naphthalenedicarboxylate 
• 122763-51-3 C₂₃H₂₄⁽²⁾H₂O₉ 
• 122763-51-3 methyl 11,11''-dideuterio-isopodophyllate 
• 75101-88-1 methyl 1,4-epoxy-3-exo-(hydroxymethyl)-6,7-(methylenedioxy)-1-(1,2-cis)-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene-2-endo-carboxylate 
• 477-67-8 epipodophyllic acid 

Relevant academic research and scientific papers

Comprehensive Synthetic Route to Eight Diastereomeric Podophyllum Lignans

An oxabicyclo compound, 9, prepared in 47percent yield through an isobenzofuran intermediate was converted with excellent regio- and stereocontrol to eight (+/-)-lignan lactones of the podophyllotoxin series.One of the eight, epiisopicropodophyllin, 36, t

Hydroxyacetals, phtalans, and isobenzofurans therefrom

A general method for the generation of isobenzofuran intermediates is described.Lithiated aromatic acetals are converted to hydroxyacetals (A) which may be cyclized to isobenzofurans by mild acid treatment through the 1-hydroxyphtalans (B).The isobenzofur

A Stereo- and Regiocontrolled Synthesis of Podophyllum Lignans

A Diels-Alder adduct of an isobenzofuran (generated in situ) and dimethyl acetylenedicarboxylate is converted by a series of controlled reductions and isomerizations to the lignans deoxy- and isodeoxypodophyllotoxin in seven stages.