118684-36-9

Upstream product

• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 58-61-7 adenosine 
• 10457-15-5 O^2'_,O3'_,O5'-tris-trimethylsilanyl-adenosine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 201225-47-0 N-{9-[(2R,3S,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-3-(2,2,2-trifluoro-acetylamino)-tetrahydro-furan-2-yl]-9H-purin-6-yl}-benzamide 
• 201225-46-9 9-[2-amino-2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl]-N⁶-benzoyladenine 
• 201225-43-6 N-[9-((2R,3S,3aS,9aR)-3-Azido-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-9H-purin-6-yl]-benzamide 
• 201225-44-7 N-[9-((2R,3S,3aS,9aR)-3-Amino-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-9H-purin-6-yl]-benzamide 
• 201225-45-8 N-[9-((2R,3S,4S,5R)-3-Amino-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-yl]-benzamide 
• 136923-03-0 Trifluoro-methanesulfonic acid (2R,3R,3aR,9aR)-2-(6-benzoylamino-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester 
• 79154-57-7 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-N₆-benzoyladenosine 
• 329014-11-1 9-(2'-O-acetyl-3'-bromo-5'-O-tert-butyldiphenylsilyl-3'-deoxy-β-D-xylofuranosyl)-6-N-benzoyl adenine 
• 80615-03-8 Acetic acid (2R,3R,5S)-2-(6-benzoylamino-purin-9-yl)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-3-yl ester 
• 77244-83-8 6-N-benzoyl-9-(5-O-tert-butyldiphenylsilyl-β-D-ribofuranosyl)adenine 
• 77244-85-0 2'-O-acetyl-N⁶-benzoyl-3'-deoxyadenosine 
• 76902-49-3 N-(9-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide 
• 4546-55-8 N-benzoyladenosine 

Relevant academic research and scientific papers

Preparation N6 -Improved method for benzoyl - D D-adenosine

The invention relates to an improved process for preparing N6-benzoyl-D-adenosine, which is characterized in that in a generated trimethyl silicon-based protected D-adenosine reaction system, benzoyl chloride is added for a benzoylation reaction, the crud

An improved transient method for the synthesis of N-benzoylated nucleosides

The Jones' transient method for the synthesis of N-benzoylated nucleosides is improved by reducing the amounts of chlorotrimethylsilane (TMSCl) and benzoyl chloride to nearly equivalent quantities. The easy work-up and high yields of products are the major advantages of this approach. Jones' method is further simplified by omitting the addition of ammonium hydroxide. The utility of this modification for the preparation of some useful protected nucleosides is also presented.

Efficient synthesis of protected 3′-deoxyadenosine and 3′-deoxyguanosine from adenosine and guanosine

Highly efficient synthesis of protected 3′-deoxyadenosine and 3′-deoxyguanosine from adenosine and guanosine were described. The 2′,3′-diol of protected adenosine and guanosine were reacted with α-acetoxyisobutyryl bromide to yield 9-(2′-O-acetyl-3′-bromo

Synthesis and properties of modified oligodeoxyribonucleotides containing 9-(2-amino-2-deoxy-β-D-arabinofuranosyl)adenine

The synthesis of modified oligodeoxyribonucleotides containing 2'- amino-2'-deoxyarabinoadenosine residues (aA(n)) was carried out by means of the standard phosphoramidite chemistry. A high reactivity of such compounds to electrophilic reagents was shown.