76929-37-8Relevant articles and documents
Direct synthesis of polysubstituted 2-aminothiophenes by Cu(ii)-catalyzed addition/oxidative cyclization of alkynoates with thioamides
Ge, Li-Shi,Wang, Zheng-Lin,An, Xing-Lan,Luo, Xiaoyan,Deng, Wei-Ping
, p. 8473 - 8479 (2014/12/10)
A facile and direct synthetic method was developed for the construction of structurally important 2-aminothiophenes in moderate to excellent yields (up to 91%), via Cu(ii)-catalyzed addition/oxidative cyclization of readily available thioamides with alkynoates under an air atmosphere. This journal is
Two-carbon extension of N,N-disubstituted amides with bis(trimethylsilyl) thioketene affording N,N-disubstituted 3-oxothioamides
Tsuchiya, Tohru,Oishi, Akihiro,Shibuya, Isao,Taguchi, Yoichi,Honda, Kazumasa
, p. 1621 - 1622 (2007/10/03)
N,N-Disubstituted alkanamides cleanly react with bis(trimethylsilyl)thioketene to form N,N-disubstituted 2-trimethylsilyl-3-trimethylsilyloxyalk-2-enethioamides, which upon acid hydrolysis give N,N-disubstituted 3-oxoalkanethioamides.