76951-66-1

Basic information

• Product Name: 1,2:3,4-di-O-isopropylidene-6-O-trityl-α-D-galactopyranose
• Synonyms: 1,2:3,4-di-O-isopropylidene-6-O-trityl-α-D-galactopyranose
• CAS NO: 76951-66-1
• Molecular Weight: 502.607
• Mol File: 76951-66-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,2:3,4-di-O-isopropylidene-6-O-trityl-α-D-galactopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2:3,4-di-O-isopropylidene-6-O-trityl-α-D-galactopyranose(76951-66-1)
• EPA Substance Registry System: 1,2:3,4-di-O-isopropylidene-6-O-trityl-α-D-galactopyranose(76951-66-1)

Safety Data

• Hazardous Substances Data: 76951-66-1(Hazardous Substances Data)

Upstream product

• 76-83-5 trityl chloride 
• 4064-06-6 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose 
• 341-02-6 trityl tetrafluoroborate 
• 85326-15-4 3,4-di-O-acetyl-1,2-O-<1-(endo-cyano)ethylidene>-α-D-xylopyranose 
• 141561-63-9 (((3-methylbut-2-en-1-yl)oxy)methanetrityl)tribenzene 
• 76-84-6 triphenylmethyl alcohol 
• 312493-51-9 (((4-methoxybenzyl)oxy)methanetriyl)tribenzene 

Downstream Products

• 3646-73-9 α-D-galactopyranose 
• 60945-40-6 O¹,O²-isopropylidene-α-D-galactopyranose 
• 552-74-9 6-O-α-L-rhamnopyranosyl-D-galactose 
• 4064-06-6 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose 
• 5239-08-7 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl-(1->6)-1,2:3,4-O-diisopropylidene-α-D-galactopyranose 
• 86782-41-4 p-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-D-glucopyranoside 
• 26184-96-3 rutinose 
• 62043-20-3 1,2:3,4-di-O-isopropylidene-6-O-(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)-α-D-galactopyranose 
• 80763-58-2 1,3,4,6-tetra O-benzoyl-α-fructofuranosyl-(2->6)-1,2:3,4-di-O-isopropylidene-α-D-galactopyranoside 

Relevant articles and documents

Novel selectivity in carbohydrate reactions, IV: DABCO-mediated regioselective primary hydroxyl protection of carbohydrates

An efficient procedure for the regioselective tritylation of primary hydroxyl group of aldohexopyranosides and nucleosides using trityl chloride in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) in dichloromethane has been developed. Subsequent acetylation of the tritylated products in the same pot has been made possible, thereby providing an efficient route to the fully protected carbohydrate derivatives that can be discriminated chemoselectively.

Alternative reagents for the tritylation of alcohols

Two new tritylation reagents [viz. p-methoxybenzyl trityl ether (p-MBTE) and prenyl trityl ether (PTE)] were prepared. These two new reagents were utilized efficiently for the tritylation of alcohols, using DDQ or 20 mol% DDQ-3 eq. Mn(OAc)3. Copyright Tay

p-Methoxybenzyl trityl ether (p-MBTE): A new and improved tritylating reagent

p-Methoxybenzyl trityl ether (p-MBTE), synthesized for the first time from trityl chloride and p-methoxybenzyl alcohol, is utilized as a tritylating agent for a variety of alcohols, under neutral conditions, in 10-30 min. and excellent yields.