312493-51-9

Basic information

• Product Name: P-METHOXYBENZYL TRITYL ETHER 97
• Synonyms: P-METHOXYBENZYL TRITYL ETHER 97;1-methoxy-4-trityloxymethylbenzene
• CAS NO: 312493-51-9
• Molecular Formula: C₂₇H₂₄O₂
• Molecular Weight: 380.49
• Mol File: 312493-51-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 132-136 °C(lit.)
• Appearance: /
• CAS DataBase Reference: P-METHOXYBENZYL TRITYL ETHER 97(CAS DataBase Reference)
• NIST Chemistry Reference: P-METHOXYBENZYL TRITYL ETHER 97(312493-51-9)
• EPA Substance Registry System: P-METHOXYBENZYL TRITYL ETHER 97(312493-51-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 312493-51-9(Hazardous Substances Data)

Upstream product

• 76-83-5 trityl chloride 
• 105-13-5 4-Methoxybenzyl alcohol 
• 76-84-6 triphenylmethyl alcohol 
• 123-11-5 4-methoxy-benzaldehyde 
• 286-20-4 cyclohexane-1,2-epoxide 

Downstream Products

• 144732-43-4 (3aR,6R,6aR)-4-Methoxy-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxole 
• 38257-94-2 4-[(triphenylmethyl)oxy]butanol 
• 38257-95-3 6-(triphenylmethyloxy)-1-hexanol 
• 312493-45-1 (1S,2R,4S)-1-isopropyl-4-methyl-2-trityloxy-cyclohexane 
• 20590-53-8 1,2-O-isopropylidene-5-O-trityl-α-D-xylofuranose 
• 76951-66-1 1,2:3,4-di-O-isopropylidene-6-O-trityl-α-D-galactopyranose 
• 158576-23-9 1-tetrahydropyranyloxy-6-triphenylmethyloxyhexane 
• 157730-95-5 1-trityloxy-6-(tert-butyldimethylsilyloxy)hexane 
• 76-84-6 triphenylmethyl alcohol 

Relevant articles and documents

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Fe(III)-catalyzed trityl benzyl ether formation and disproportionation cascade reactions to yield benzaldehydes

During investigating water-compatible Lewis acids catalyzed etherifications using alcohols as alkylating reagents directly, we developed Fe(III)-catalyzed trityl benzyl ether formations irradiated by microwave. Then an in situ trityl benzyl ether formation and disproportionation cascade reaction was achieved to yield the benzaldehyde products with good functional group tolerances under neat conditions at relative higher temperatures. The substituent effects of the substrates on the etherification and disproportionation were explored by changing the substitutions on benzyl alcohols and triarylmethanols using chemical kinetic plots methods and the mechanism of the transformation was studied by crossover experiments. The etherification and disproportionation cascade process could be conveniently scaled up in laboratory without losing much efficiency.

Alternative reagents for the tritylation of alcohols

Two new tritylation reagents [viz. p-methoxybenzyl trityl ether (p-MBTE) and prenyl trityl ether (PTE)] were prepared. These two new reagents were utilized efficiently for the tritylation of alcohols, using DDQ or 20 mol% DDQ-3 eq. Mn(OAc)3. Copyright Tay