141561-63-9

Upstream product

• 76-83-5 trityl chloride 
• 556-82-1 3-methyl-2-buten-1-ol 

Downstream Products

• 141561-62-8 <(S)-2-Chloro-2-methyl-1-(trityloxymethyl)propyl>-(2,3:5,6-di-O-isopropyliden-β-D-mannofuranosyl)-disulfid 
• 141561-61-7 <(R)-2-Chloro-2-methyl-1-(trityloxymethyl)propyl>-(2,3:5,6-di-O-isopropyliden-β-D-mannofuranosyl)-disulfid 
• 20590-53-8 1,2-O-isopropylidene-5-O-trityl-α-D-xylofuranose 
• 38257-95-3 6-(triphenylmethyloxy)-1-hexanol 
• 158576-23-9 1-tetrahydropyranyloxy-6-triphenylmethyloxyhexane 
• 157730-95-5 1-trityloxy-6-(tert-butyldimethylsilyloxy)hexane 
• 312493-45-1 (1S,2R,4S)-1-isopropyl-4-methyl-2-trityloxy-cyclohexane 
• 76951-66-1 1,2:3,4-di-O-isopropylidene-6-O-trityl-α-D-galactopyranose 
• 1399679-90-3 (E)-2-methyl-4-(trityloxy)but-2-en-1-ol 
• 1399679-95-8 (E)-2-methyl-4-(trityloxy)but-2-enal 
• 1399679-69-6 (3S,4S,E)-3,5-dimethyl-7-(trityloxy)hepta-1,5-dien-4-ol 
• 1399680-27-3 (3R,6R,7S)-(3S,4S,E)-3,5-dimethyl-7-(trityloxy)hepta-1,5-dien-4-yl 3-((tert-butyldimethylsilyl)oxy)-7-((4-methoxybenzyl)oxy)-6-methyl-6-((triethylsilyl)oxy)non-8-enoate 
• 1399679-99-2 (3R,6R,7S)-(3S,4S,E)-3,5-dimethyl-7-(trityloxy)hepta-1,5-dien-4-yl-3-((tert-butyldimethylsilyl)oxy)-7-hydroxy-6-methyl-6-((triethylsilyl)oxy)non-8-enoate 

Relevant academic research and scientific papers

Catalytic asymmetric aldehyde prenylation and application in the total synthesis of (-)-rosiridol and (-)-bifurcadiol

Chiral phosphoric acid-catalyzed asymmetric aldehyde prenylation has been established using an α,α-dimethyl allyl boronic ester. The transformation provides expedient access to a wide array of aryl, heteroaryl, aryl-substituted alkenyl and primary and sec

Enantioselective total synthesis of pladienolide B: A potent spliceosome inhibitor

An enantioselective and convergent total synthesis of pladienolide B (1) is described. Pladienolide B binds to the SF3b complex of a spliceosome and inhibits mRNA splicing activity. The synthesis features an epoxide opening reaction, an asymmetric reduction of a β-keto ester, and a cross metathesis strategy for the side chain synthesis.

Alternative reagents for the tritylation of alcohols

Two new tritylation reagents [viz. p-methoxybenzyl trityl ether (p-MBTE) and prenyl trityl ether (PTE)] were prepared. These two new reagents were utilized efficiently for the tritylation of alcohols, using DDQ or 20 mol% DDQ-3 eq. Mn(OAc)3. Copyright Tay