769961-91-3

Upstream product

• 1462-37-9 bromoethyl-2-benzyl ether 
• 622-08-2 2-Benzyloxyethanol 
• 674-82-8 4-methyleneoxetan-2-one 
• 769961-90-2 (2-benzyloxy-ethyl)-(1-methyl-1-phenyl-ethyl)-amine 

Downstream Products

• 192942-82-8 4-benzyloxy-pyrrolidin-2-one 
• 420137-14-0 3-(benzyloxy)-pyrrolidine 
• 769961-92-4 4-benzyloxy-1-(1-methyl-1-phenyl-ethyl)-pyrrolidin-2-one 

Relevant academic research and scientific papers

Cumyl: A better N-protecting group of α-diazo acetamides for intramolecular C-H insertion reaction and its application in the synthesis of pregabalin and 3-benzyloxy pyrrolidine

Via intramolecular C-H insertion of N-cumyl α-diazo acetamides, γ-lactams were efficiently synthesized with excellent regioselectivity. A concise route for the preparation of pregabalin (79% overall yield) and 3-benzyloxy pyrrolidine (21% overall yield) were reported.