77070-79-2

Usage

Uses

Used in Chemical Synthesis:
3-Pentanone, 1,1,5,5-tetraethoxyis used as a reagent in the synthesis of various organic compounds due to its unique reactivity and properties. It facilitates the formation of desired products in chemical reactions, making it a valuable component in research and industrial applications.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 3-Pentanone, 1,1,5,5-tetraethoxyis utilized as a key intermediate in the production of various drugs. Its unique chemical structure allows for the development of new pharmaceutical compounds with specific therapeutic properties.
Used in Flavor and Fragrance Industry:
3-Pentanone, 1,1,5,5-tetraethoxyis employed as a building block for creating unique flavors and fragrances. Its versatile chemical properties enable the development of novel scents and tastes for use in various consumer products.
Used in Specialty Chemicals Production:
3-Pentanone, 1,1,5,5-tetraethoxyis also used in the production of specialty chemicals, where its unique properties and reactivity contribute to the development of high-value products for specific applications in various industries.

Upstream product

• 122-51-0 orthoformic acid triethyl ester 
• 67-64-1 acetone 
• 1478-41-7 diethoxycarbonium fluoroborate 
• 20082-91-1 4,4-diethoxybutan-2-one 
• 135203-25-7 1,1-diethoxy-3-trimethylsilyloxy-3-butene 

Downstream Products

• 171193-54-7 3-dodecyl-1,1,5,5-tetraethoxy-3-pentanol 
• 108-96-3 4-pyridone 
• 108-97-4 4-pyrone 
• 135203-27-9 1,5-diethoxypentane-1,4-dien-3-one 

Relevant academic research and scientific papers

Tetrahydro-4 H-pyran-4-one: From the Laboratory Scale to Pilot Plant Manufacture

This study describes our recent efforts to find an efficient and scalable route to tetrahydro-4H-pyran-4-one using the commercially available starting materials. The route scouting work and the full development of an efficient access to the target are described. This work culminated in the preparation of above 20 kg of the title compound in our pilot plant facility.

Concise two-step synthesis of γ-pyrone from acetone

γ-Pyrone (1) is readily accessible in 59% overall yield via 1,1,5,5-tetraethoxy-3-pentanone (10b) and subsequent acidic hydrolysis. The synthesis enables an easy scale up, as demonstrated for intermediate 10b.

SYNTHESIS OF 1,1-DIETHOXY-3-TRIMETHYLSILYLOXY-3-BUTENE AND STUDY OF ITS CONDENSATION WITH ACETALS AND ETHYL ORTHOFORMATE

1,1-Diethoxy-3-trimethylsilyloxy-3-butene was synthesized by the action of a mixture of trimethylchlorosilane, sodium iodide, and triethylamine on 1,1-diethoxy-3-butanone.Its condensation with orthoformic ester and acetaldehyde, butyraldehyde, and isovaleraldehyde acetals in the presence of zinc chloride as catalyst was investigated.The synthesis of 1,1,5,5-tetraethoxy-3-butanone and a series of 1,1,5-triethoxy-3-alkanones was realized.

A Procedure for Diethoxymethylation of Ketones

Reaction of a number of ketones with diethoxycarbenium fluoroborate in the presence of N,N-diisopropylethylamine at low temperature in methylene chloride results in a preparatively useful conversion to α-(diethoxymethyl) ketones.The method is compatible with arene, nitrile, chloride, and ester functional groups.With unsymmetrically substituted ketones, it is regioselective for the less substituted α-position.In favorable cases α,α'-dialkylation occurs.Conjugated ketones react normally at the saturated position adjacent to the carbonyl group.The mechanism of the reaction is considered.