20082-91-1

Usage

Uses

Used in Organic Synthesis:
4,4-Diethoxybutan-2-one is used as a synthetic intermediate for the production of various chemical products in the laboratory. Its reactivity and versatility make it a valuable substance in organic synthesis.
Used in Research and Development:
The chemical and physical properties of DEBK render it a valuable substance in several areas of research and application. Its unique molecular structure and reactivity contribute to the development of new compounds and materials in the scientific community.
Used in Pharmaceutical Industry:
4,4-Diethoxybutan-2-one can be used as a building block or precursor in the synthesis of pharmaceutical compounds. Its ability to react with other molecules allows for the creation of new drug candidates with potential therapeutic applications.
Used in Flavor and Fragrance Industry:
Due to its unique chemical structure, DEBK may also be used in the flavor and fragrance industry to create new scents or enhance existing ones. Its reactivity can be utilized to modify or create novel aroma compounds.

InChI:InChI=1/C8H16O3/c1-4-10-8(11-5-2)6-7(3)9/h8H,4-6H2,1-3H3

Upstream product

• 64-17-5 ethanol 
• 4643-20-3 (E)-4-chloro-3-buten-2-one 
• 97674-28-7 ethoxy-3-methyl-1,2-dioxolane 
• 1478-41-7 diethoxycarbonium fluoroborate 
• 67-64-1 acetone 
• 41125-09-1 3-oxo-butyraldehyde; sodium enolate 
• 122-51-0 orthoformic acid triethyl ester 
• 51731-17-0 trans-4-methoxy-3-buten-2-one 
• 1833-53-0 2-(Trimethylsilyloxy)propene 
• 5930-98-3 4-trimethylsilyl-3-butyn-2-one 
• 141-52-6 sodium ethanolate 
• 5436-21-5 acetylacetaldehyde dimethyl acetal 
• 41616-93-7 1,1,3,3-tetraethoxy-butane 
• 74-96-4 ethyl bromide 

Downstream Products

• 3284-51-3 ethyl 5-methyl-1H-pyrrole-2-carboxylate 
• 779-90-8 1,3,5-triacetylbenzene 
• 4241-27-4 2-hydroxy-6-methylnicotinonitrile 
• 23074-57-9 4-ethoxybut-3-en-2-one 
• 75-00-3 chloroethane 
• 88972-21-8 (1-Ethoxy-3-oxo-butyl)-phosphonic acid diethyl ester 
• 762-04-9 phosphonic acid diethyl ester 
• 74-87-3 methylene chloride 
• 89206-77-9 [1-(Benzo[1,3,2]dioxaphosphol-2-yloxy)-3,3-diethoxy-1-methyl-propyl]-phosphonic acid dimethyl ester 
• 89206-78-0 2-<1-(diethoxyphosphinyl)-3,3-diethoxy-1-methylpropoxy>-1,3,2-benzodioxaphosphole 
• 74399-43-2 (trimethyl-2,6,6 cyclohexene-1 yl)-9 diethoxy-1,1 dimethyl-3,7 hydroxy-7 nonatriene-3,5,8 
• 77070-79-2 1,1,5,5-tetraethoxy-3-pentanone 
• 122834-82-6 Benzoic acid N'-(2-benzoyl-5-methyl-3,4-dihydro-2H-pyrazol-3-yl)-hydrazide 
• 87005-16-1 2-nitro-3-oxobutanal 

Relevant academic research and scientific papers

Ozonolysis of Enol Ethers. Formation of 3-Alkoxy-1,2-dioxolanes by Concerted Addition of a Carbonyl Oxide to an Enol Ether

The ozonolyses of methyl vinyl ether, ethyl vinyl ether, and ethyl isopropenyl ether were studied in a variety of solvents.Alkoxy-1,2,4-trioxolanes and alkoxy-1,2-dioxolanes were the main products in pentane and ester solvents.These products arose from the carbonyl oxide (H2COO) produced upon ozonolysis undergoing 1,3-cycloaddition reactions with esters and activated olefins (enol ethers).From additional trapping experiments, the following relative dipolarophilicities toward the carbonyl oxide were inferred: aldehydes > enol ethers > esters - ca. ketones.Ozonolysis of stereolabeled ethyl vinyl-2-d1 ether gave ethoxy-1,2-dioxolane with retention of the alkene configuration at the -CHDCH(OEt)- linkage.This is the first example where stereospecificity, implying concertedness, has been directly observed for a reaction of a carbonyl oxide with a substrate.These results are consistent with the Criegee mechanism and extend it to the ozonolysis of enol ethers.

3,3-SPIROINDOLINONE DERIVATIVES

There are provided compounds of the general formulas wherein X, Y, R1, R2, R3, R4 and R5 are as described herein. The compounds exhibit anticancer activity.

Direct organocatalytic hydroalkoxylation of α,β-unsaturated ketones

The direct addition of a variety of alcohols to in situ activated olefins was observed in the presence of mild bifunctional amine/acid catalysts. Unlike existing methods, the reactions proceed at room temperature and in the absence of transition metals. The use of simple commercially available catalysts, amines and acids makes this an attractive method for the preparation of β-alkoxy ketones, which are prevalent targets and intermediates in organic synthesis.

DERIVATIVES OF BIACETYLENE. XLV. REACTION OF BIACETYLENE AND 1-METHOXY-1-BUTEN-3-YNE WITH DIETHYLENE GLYCOL

The nucleophilic addition of diethylene glycol to biacetylene and methoxybutenyne and the electrophilic reaction of methoxybutenyne with diethylene glycol were investigated.In the presence of alkali two molecules of diethylene glycol add to biacetylene and methoxybutenyne.In the presence of mercury sulfate and water the reaction leads to the formation of a linear β-keto acetal.

A Procedure for Diethoxymethylation of Ketones

Reaction of a number of ketones with diethoxycarbenium fluoroborate in the presence of N,N-diisopropylethylamine at low temperature in methylene chloride results in a preparatively useful conversion to α-(diethoxymethyl) ketones.The method is compatible with arene, nitrile, chloride, and ester functional groups.With unsymmetrically substituted ketones, it is regioselective for the less substituted α-position.In favorable cases α,α'-dialkylation occurs.Conjugated ketones react normally at the saturated position adjacent to the carbonyl group.The mechanism of the reaction is considered.

Chemistry of enol ethers. LI. Reaction of vinyl silyl ethers with orthoformic esters

The silyl ethers of enolic forms of ketones react with orthoformates in the presence of zinc chloride at catalyst to form β-ketoacetals.The analogous reaction with the silyl ethers of enolic forms of aldehydes leads to the formation of the tetraacetals of 1,3-dialdehydes.