3364-76-9

Usage

Uses

Used in Organic Synthesis:
4-(chloromethyl)-1,3-thiazole is used as a building block in the preparation of various pharmaceuticals, agrochemicals, and materials, leveraging its unique structural features to contribute to the development of new compounds with desired properties.
Used in Pharmaceutical Industry:
4-(chloromethyl)-1,3-thiazole is utilized as a key intermediate for the synthesis of complex organic molecules with potential therapeutic applications, including those with antibacterial and anti-inflammatory properties, due to the presence of the biologically active thiazole ring.
Used in Agrochemical Industry:
In the agrochemical sector, 4-(chloromethyl)-1,3-thiazole is employed as a precursor in the development of new compounds intended for use in agriculture, potentially contributing to the creation of more effective and targeted pest control agents.
Safety Considerations:
It is crucial to handle 4-(chloromethyl)-1,3-thiazole with caution, as it is a potential irritant to the skin, eyes, and respiratory system. Proper handling includes using it in a well-ventilated area and wearing appropriate protective equipment to minimize health risks.

InChI:InChI=1/C4H6N2S/c5-1-4-2-7-3-6-4/h2-3H,1,5H2

Upstream product

• 693-95-8 4-Methylthiazole 
• 7709-58-2 4-(chloromethyl)thiazole hydrochloride 
• 115-08-2 thiocarboxamide 
• 534-07-6 1,3-Dichloroacetone 

Downstream Products

• 90724-59-7 thiazol-4-ylmethyl acetate 
• 118001-74-4 4-(4-thiazolylmethoxy)benzaldehyde 
• 191589-72-7 3-Oxo-3-phenyl-2-thiazol-4-ylmethyl-propionic acid ethyl ester 
• 3364-80-5 1,3-thiazole-4-carbaldehyde 
• 868541-94-0 2-[N-(diphenylmethylene)amino]-3-(1,3-thiazol-4-yl)propanoic acid, tert-butyl ester 
• 865869-55-2 ethyl 3-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-1-{4-[(1,3-thiazol-4-ylmethyl)oxy]phenyl}-1H-pyrazole-4-carboxylate 
• 1187464-95-4 N-[(2Z)-5-tert-butyl-3-(1,3-thiazol-4-ylmethyl)-1,3,4-thiadiazol-2(3H)-ylidene]-5-chloro-2-methoxybenzamide 
• 1240521-20-3 methyl N-(((1,1-dimethylethyl)oxy)carbonyl)-N-(1,3-thiazol-4-ylmethyl)-L-phenylalaninate 
• 1421837-16-2 N-((4-chlorophenyl)(phenyl)methyl)-2-(4-(thiazol-4-ylmethoxy)phenyl)acetamide 
• 1065641-03-3 5-chloro-2-methoxy-N-[(2Z)-5-methyl-3-(1,3-thiazol-4-ylmethyl)-1,3-thiazol-2(3H)-ylidene]benzamide 
• 1065641-09-9 5-chloro-N-[(2Z)-5-chloro-3-(1,3-thiazol-4-ylmethyl)-1,3-thiazol-2(3H)-ylidene]-2-methoxybenzamide 

Relevant academic research and scientific papers

NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR

[Problem] The present invention addresses the problem of providing a novel compound. The present invention also addresses the problem of providing an OCT3 detection agent or an OCT3 activity inhibitor, which comprises the novel compound. [Solution] A compound represented by formula (A), a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof. ????????R1-R2-R3-R4?????(A)

Structure-activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350)

The HIV protease inhibitor (PI) ritonavir (RTV) has been widely used as a pharmacoenhancer for other PIs, which are substrates of cytochrome P450 3A (CYP3A). However the potent anti-HIV activity of ritonavir may limit its use as a pharmacoenhancer with other classes of anti-HIV agents. Ritonavir is also associated with limitations such as poor physicochemical properties. To address these issues a series of compounds with replacements at the P2 and/or P3 region was designed and evaluated as novel CYP3A inhibitors. Through these efforts, a potent and selective inhibitor of CYP3A, GS-9350 (cobicistat) with improved physiochemical properties was discovered.

QUINAZOLINE DERIVATIVES AS ANTICANCER AGENTS

A quinazoline derivative of the Formula I: wherein the substituents are as defined in the text for use in the production of an anti proliferative effect which effect is produced alone or in part by inhibiting erbB2 receptor tyrosine kinase in a warm blood

TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS

The present invention provides a compound of the formula: Formula I or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or ex

C (2) -HETEROARYLMETHYL-C (4) -METHOXYMETHYL ACYL PYRROLIDINE COMPOUNDS AND THEIR USE FOR TREATING VIRAL INFECTIONS, ESPECIALLY HEPATITIS C VIRUS

Anti-viral agents of Formula (Ia): wherein A represents hydroxyl; D represents 4-tert-butyl-3-ethenylphenyl or 4-tert-butyl-5-ethenyl-2-fluorophenyl; E represents 1,3-thiazol-2-yl; G represents methoxymethyl; J represents 1,3-thiazol-4-ylmethyl or 1H-pyra

C (2) -HETEROARYLMETHYL-C (4) -PYRAZIN-2-YL ACYL PYRROLIDINE COMPOUNDS AND THEIR USER FOR TREATING VIRAL INFECTIONS, ESPECIALLY HEPATITICS C (HCV)

Anti-viral agents of Formula (Ia) : wherein A represents hydroxy; B represents -C(O)R3; D represents 1,3-thiazol-2-yl; E represents pyrazin-2-yl; G represents 1,3-thiazol-4-ylmethyl or 1H-pyrazol-1-ylmethyl; R3 represents 4-tert-buty

PYRROLIDINE DERIVATIVES FOR TREATING VIRAL INFECTIONS

Anti-viral agents of Formula (Ia): wherein A represents hydroxy; D represents 3-bromo-4-tert-butylphenyl or 5-bromo-4-tert-butyl-2-fluorophenyl; E represents 1,3-thiazol-2-yl or 5-methylisoxazol-3-yl; G represents methoxymethyl; J represents 1,3-thiazol-4

C (2) -HETEROARYLMETHYL-C (4) -PYRAZINYL-2-YL ACYL PYRROLIDINE COMPOUNDS AND THEIR USE FOR TREATING VIRAL INFECTIONS, ESPECIALLY HEPATITIS C VIRUS

Anti-viral agents of Formula (Ia) : wherein A represents hydroxy; B represents -C(O)R3; D represents 1,3-thiazol-2-yl or 5-methylisoxazol-3-yl; E represents pyrazin-2-yl; G represents 1,3-thiazol-4-ylmethyl or 1H-pyrazol-1-ylmethyl; R3 /s

DERIVATIVES OF THIOPHENE CARBOXILIC ACID AS ANTIVIRAL AGENT

Anti-viral agents of compounds of Formuta (I) : wherein A, R1, R2 and R3 are as defined in the specification, processes for their preparation and their use in HCV treatment are provided.

4- (PYRAZINE-2-YL) -PYRROLIDINE-2-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF AS HEPATITIS C VIRUS INHIBITORS

Anti-viral agents of Formula (Ia) wherein: A represents hydroxy; B represents C(O)R3 wherein R3 is 4-tert-butyl-3-methoxyphenyl; D represents 1,3-thiazol-2-yl or 5-methyl-1,3-thiazol-2-yl; E represents pyrazin-2-yl; G represents 1,3-