77134-19-1Relevant academic research and scientific papers
Triazolopyridines. Part 27.1 the preparation of novel 6,7-dihydro[1,2,3] triazolo[1,5-a]pyridines
Abarca, Belen,Adam, Rosa,Ballesteros, Rafael
scheme or table, p. 319 - 327 (2010/08/19)
A very efficient synthesis of the unknown family of 6,7-dihydro[1,2,3] triazolo[1,5-α]pyridines from [1,2,3]triazolo[1,5-α]pyridines have been developed, and a mechanism for their formation has been proposed. Their behaviour with NBS to give 4,5-dibromo substituted-4,5,6,7-tetrahydro-[1,2,3] triazolo[1,5-α]pyridines is studied.
Triazolopyridines. Part 2. Preparation of 7-Substituted Triazolopyridines by Directed Lithiation
Jones, Gurnos,Sliskovic, D. Robert
, p. 967 - 972 (2007/10/02)
The lithiation reactions of 1,2,3-triazolopyridine (1) to give the 7-lithio-derivative (4; R = Li), and of its 7-methyl derivative (16) to give the 7-lithiomethyl compound, are described.These lithium derivatives react with electrophiles, notably a
[1,2,3]Triazolo[1,5-a]pyridine - a synthon for 6-substituted pyridine-2-carboxaldehydes
Jones, Gurnos,Sliskovic, D.Robert
, p. 4529 - 4530 (2007/10/02)
[1,2,3]Triazolo[1,5-a]pyridine (1) is lithiated in position 7; the lithio derivative is used to synthesize triazolopyridinyl alcohols (6) which can be converted into 6-substituted pyridine-2-aldehydes (3).
