771573-22-9

Usage

Uses

Used in Pharmaceutical Industry:
3-(Methylsulfonyl)Benzenemethanamine is used as an intermediate compound for the synthesis of various pharmaceutical products. Its unique structure, containing both sulfur and nitrogen atoms, makes it a valuable building block in the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
3-(Methylsulfonyl)Benzenemethanamine is used as a key component in the synthesis of a wide range of chemical compounds. Its aromatic amine nature allows for various chemical reactions, making it a versatile starting material for the production of different organic molecules.
Used in Research and Development:
3-(Methylsulfonyl)Benzenemethanamine is used as a research compound in academic and industrial laboratories. Its unique properties and potential applications make it an interesting subject for studies in organic chemistry, medicinal chemistry, and materials science.

Upstream product

• 22821-75-6 3-(methylsulfonyl)benzonitrile 
• 866005-41-6 1-azidomethyl-3-methanesulfonyl-benzene 
• 18698-73-2 [3-(methylthio)phenyl]acetic acid 
• 35216-39-8 3-(methylsulfonyl)aniline 
• 2976-32-1 1-methanesulfonyl-3-nitro-benzene 
• 90721-40-7 3-methanesulfanyl benzoic acid methyl ester 
• 59083-33-9 (3-methylsulfanyl-phenyl)-methanol 
• 866005-39-2 1-azidomethyl-3-methylsulfanyl-benzene 

Downstream Products

• 1451993-67-1 C₁₇H₁₈N₄O₃S₂ 
• 1021873-73-3 5-chloro-2-imino-1-[3-(methylsulfonyl)benzyl]-1,2-dihydropyridine-3-carboxamide monohydrochloride 
• 1611472-31-1 8-(4-chlorophenyl)-N-(3-(methylsulfonyl)benzyl)-1,6-naphthyridine-2-carboxamide 
• 1436383-97-9 3-bromo-2-methyl-N-[(3-methylsulfonylphenyl)methyl]imidazo[1,2-a]pyrazin-8-amine 
• 1061358-73-3 2-chloro-N-(3-(methylsulfonyl)benzyl)-5-(trifluoromethyl)pyridin-4-amine 
• 1033575-56-2 2-(2-chlorophenyl)-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid 3-methanesulfonyl-benzylamide 

Relevant academic research and scientific papers

SUBSTITUTED 2- AMIDOQUINAZOL-4-ONES AS MATRIX METALLOPROTEINASE-13 INHIBITORS

The present invention provides a novel amide derivative having a matrix metalloproteinase inhibitory activity, and useful as a pharmaceutical agent, which is a compound represented by the formula (I) wherein ring A is an optionally substituted, nitrogen containing heterocycle, ring B is an optionally substituted monocyclic homocycle or an optionally substituted monocyclic heterocycle, Z is N or NR1 (R1 is a hydrogen atom or an optionally substituted hydrocarbon group), is a single bond or a double bond, R2 is a hydrogen atom or an optionally substituted hydrocarbon group, X is an optionally substituted spacer having 1 to 6 atoms, ring C is (1) an optionally substituted homocycle or (2) an optionally substituted heterocycle other than a ring represented by (II) (X′ is S, O, SO, or CH2), and at least one of ring B and ring C has substituent(s), provided that N-{(1S,2R)-1-(3,5-difluorobenzyl)-3-[(3-ethylbenzyl)amino]2 hydroxypropyl}5,6 dimethyl 4 oxo 1,4 dihydrothieno[2,3-d]pyrimidine-2-carboxamide is excluded, or a salt thereof.

PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a] PYRIDINE DERIVATIVES

This application relates to compounds of the general Formula I and salts thereof, wherein X, R1A, R1B, R2, R3, R4, and R5 are as defined herein. The application also relates to compositions and methods of treatment of hyperproliferative diseases or disorders.

Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists

The structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues have been investigated as TRPV1 receptor antagonists. The 2-halogen analogues showed enhanced antagonism compared to the prototype antagonist.