2976-32-1

Basic information

• Product Name: Methyl 3-nitrophenyl sulfone
• Synonyms: 1-(Methylsulfonyl)-3-nitrobenzene;Methyl 3-nitrophenyl sulfone;Methyl m-nitrophenyl sulfone
• CAS NO: 2976-32-1
• Molecular Formula: C₇H₇NO₄S
• Molecular Weight: 201.1998
• Mol File: 2976-32-1.mol
• Article Data: 23

Chemical Properties

• Melting Point: 146 °C
• Boiling Point: 392.8°Cat760mmHg
• Flash Point: 191.3°C
• Appearance: /
• Density: 1.406g/cm³
• Vapor Pressure: 5.06E-06mmHg at 25°C
• Refractive Index: 1.559
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl 3-nitrophenyl sulfone(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-nitrophenyl sulfone(2976-32-1)
• EPA Substance Registry System: Methyl 3-nitrophenyl sulfone(2976-32-1)

Safety Data

• Hazardous Substances Data: 2976-32-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 60, p. 7348, 1995 DOI: 10.1021/jo00127a048

InChI:InChI=1/C7H7NO4S/c1-13(11,12)7-4-2-3-6(5-7)8(9)10/h2-5H,1H3

Upstream product

• 3959-23-7 benzenesulfonylacetic acid 
• 21731-56-6 1-Amino-4-methylsulphonyl-2-nitrobenzene 
• 6655-77-2 3-nitrophenylsulfonohydrazide 
• 868-85-9 Dimethyl phosphite 
• 645-00-1 m-iodonitrobenzene 
• 20277-69-4 sodium methansulfinate 
• 121-51-7 3-nitrobenzenesulphonyl chloride 
• 62696-04-2 TBHP 
• 110964-79-9 4-methanesulfonyl-2-nitro-benzoic acid 
• 2524-76-7 1-(methylsulfanyl)-3-nitrobenzene 
• 35216-39-8 3-(methylsulfonyl)aniline 
• 54029-50-4 acetic acid-(4-methanesulfonyl-2-nitro-anilide) 
• 22821-80-3 N-(4-methanesulfonylphenyl)acetamide 
• 13257-95-9 3-nitrobenzenesulfinic acid 

Downstream Products

• 14763-61-2 3-(methylsulfonyl)phenol 
• 43032-67-3 1-methanesulfonyl-3-methoxy-benzene 
• 3112-85-4 methylphenylsulfonate 
• 62606-01-3 3-iodo-5-(methylsulfonyl)aniline 
• 150296-24-5 3-methylsulfonylbenzamidine hydrochloride 
• 771573-22-9 1-[3-(methylsulfonyl)phenyl]methanamine 
• 58202-85-0 acetic acid-(3-methanesulfonyl-anilide) 
• 22821-75-6 3-(methylsulfonyl)benzonitrile 
• 122567-49-1 Bis-(2-chloro-ethyl)-(3-methanesulfonyl-phenyl)-amine 
• 125802-65-5 (9-Benzyl-2-chloro-9H-purin-6-yl)-(3-methanesulfonyl-phenyl)-amine 
• 208191-64-4 2-methanesulfonyl-4-nitro-phenol 
• 62606-16-0 1-iodo-3-(methylsulfonyl)-5-nitrobenzene 
• 105004-02-2 (4-methylsulfonyl-2-nitro)phenylacetonitrile 
• 89303-52-6 1-Benzenesulfonylmethyl-4-methanesulfonyl-2-nitro-benzene 

Relevant articles and documents

High Chemoselectivity in the Construction of Aryl Methyl Sulfones via an Unexpected C-S Bond Formation between Sulfonylhydrazides and Dimethyl Phosphite

A highly chemoselective route to aryl methyl sulfones via an unexpected C S bond formation between sulfonylhydrazides and dimethyl phosphite catalyzed by NaI under mild conditions has been established. This transformation provides an alternative and metal-free pathway to acquire various aryl methyl sulfones in good to excellent yields. Notably, dimethyl phosphite was employed as a stable and readily available alkyl source.

Copper-catalyzed: S -methylation of sulfonyl hydrazides with TBHP for the synthesis of methyl sulfones in water

A copper-catalyzed S-methylation of sulfonyl hydrazides with TBHP was efficiently developed, providing a variety of methyl sulfones with good to excellent yields. The reaction can be carried out in water smoothly without any ligand or additive under mild conditions and this catalyst-in-water can be recycled several times.

Synergistic combination of multi-ZrIV cations and lacunary keggin germanotungstates leading to a gigantic Zr24-cluster- Substituted Polyoxometalate

Synergistic directing roles of six lacunary fragments resulted in an unprecedented Zr24-cluster substituted poly(polyoxotungstate) Na 10K22[Zr24O22(OH) 10(H2O)2(W2O10H) 2(GeW9O34)4(GeW8O 31)2]·85H2O (Na10K 22·1·85H2O), which contains the largest [Zr24O22(OH)10(H2O)2] (Zr24) cluster in all the Zr-based poly(polyoxometalate)s to date. The most remarkable feature is that the centrosymmetric Zr24-cluster- based hexamer contains two symmetry-related [Zr12O 11(OH)5(H2O)(W2O10H) (GeW9O34)2(GeW8O31)] 16- trimers via six μ3-oxo bridges and was simultaneously trapped by three types of different segments of B-α-GeW9O34, B-α-GeW8O 31, and W2O10. The other interesting characteristic is that there are two pairs of intriguing triangular atom alignments: one is composed of the Zr(2,4,6,8,11) and W21 atoms and the other contains the Ge(1-3), Zr(3,5,7,9,10,12) and W26 atoms, and the Zr5 atom is inside the triangle; a linking mode is unobserved. The oxygenation reactions of thioethers by H2O2 were evaluated when Na 10K22·1·85H2O served as a catalyst. Results show that it is an effective catalyst for oxygenation of thioethers by H2O2. The unique redox property of oxygen-enriched polyoxotungstate fragments and Lewis acidity of the Zr cluster imbedded in Na10K22·1·85H2O provide a sufficient driving force for the catalytic conversion from thioethers to sulfoxides/sulfones.