77191-37-8Relevant articles and documents
Preparation method and application of 4-hydroxy-2-oxo-1-pyrrolidine acetic acid
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Paragraph 0034-0057, (2021/05/05)
The invention provides a preparation method of 4-hydroxy-2-oxo-1-pyrrolidine acetic acid, and the preparation method comprises the following steps: mixing oxiracetam and a lithium compound to react, so as to obtain the 4-hydroxy-2-oxo-1-pyrrolidine acetic acid. The preparation method provided by the invention is simple to operate, high in yield, high in purity and simple and convenient in post-treatment.
An efficient synthesis of racemic 4-hydroxy-2-oxo-1-pyrrolidineacetamide (oxiracetam) using tetramic-acid intermediates
Laffan,Banziger,Duc,Evans,McGarrity,Meul
, p. 892 - 900 (2007/10/02)
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