77202-08-5

Upstream product

• 77202-04-1 3-Methyl-1H-pyrazol-1-amin 
• 77202-03-0 5-Methyl-1H-pyrazol-1-amin 
• 111963-98-5 3-isopropenyl-6-methylcycloheptanone 
• 1453-58-3 3-Methylpyrazole 

Downstream Products

• 25536-14-5 methyl-2 cyclopentanopyridine 
• 66510-53-0 2-methyl-5,6,7,8,9,10,11,12,13,14-decahydrocyclododeca[b]pyridine 
• 710-40-7 5-hexyl-2-methylpyridine 
• 3256-88-0 5-phenyl-2-picoline 
• 702-16-9 5-butyl-2-methylpyridine 
• 60611-85-0 2-methyl-5-benzylpyridine 
• 157993-44-7 2-methyl-5-phenethylpyridine 
• 52535-38-3 2-methyl-5-undecylpyridine 
• 99939-19-2 2-Amino-3-hydroxycrotonamid 

Relevant academic research and scientific papers

Reactions of N-Aminopyrazoles with Halogenating Reagents and Synthesis of 1,2,3-Triazines

Reactions of N-aminopyrazoles with halogenating reagents (Cl2, Br2, I2, BrCl, ICl, IBr, N-chlorosuccinimide, and N-bromosuccinimide) were examined.Some of these reagents preferentially lead to oxidation of the amino group to give the corresponding 1,2,3-triazines as major products, while others mainly gave either or both of 1-amino-4-halopyrazoles and 5-halo-1,2,3-triazines as the result of halogenation of the 4-position of the pyrazole ring prior to the oxidation of the amino group.In some cases, the oxidation of the amino group and the halogenation of the pyrazole ring proceeded concurrently to form not only the unhalogenated triazines but also the 1-amino-4-halopyrazoles and the 5-halotriazines.Various reagents and reaction conditions were explored to utilize the reaction for the synthesis of halogenated and unhalogenated 1,2,3-triazines.Keywords - 1,2,3-triazine; halo-1,2,3-triazine; pyrazole; 1-aminopyrazole; 1-aminohalopyrazole; synthesis; oxidation; halogenation; ring expansion

SYNTHESIS OF SESQUITERPENE ALKALOIDS, GUAIPYRIDINE, EPIGUAIPYRIDINE AND RELATED COMPOUNDS

Synthesis of sesquiterpene alkaloids, guaipyridine, epiguaipyridine and related compounds, was accomplished by application of Diels-Alder reaction of 1,2,3-triazine with enamines.

1,2,3-Triazines,III. - Synthesis of N-Aminopyrazoles and their Oxidation to 1,2,3-Triazines. Molecular Structure of 1,2,3-Triazine

Oxidation of the N-aminopyrazoles 4a-i affords the 1,2,3-triazines 5a-i.Spectra and reactions - such as oxidation, reduction, and cycloaddition reactions - of some 1,2,3-triazines 5 are described.The X-ray analysis of 5a is presented.

Oxidation of 1-Aminopyrazoles and Synthesis of 1,2,3-Triazines

Unsubstituted and various substituted monocyclic 1,2,3-triazines were synthesized from 1-aminopyrazoles by oxidation with lead tetraacetate, lead dioxide-CF3CO2H, and/or nickel peroxide-AcOH.

1,2,3-Triazine

1,2,3-Triazine was obtained by nickel peroxide oxidation of N-aminopyrazole.

Synthesis, Oxidation, and Reduction of Monocyclic 1,2,3-Triazines

Alkyl substituted monocyclic 1,2,3-triazines and their 1- and 2-oxides have been synthesized; catalytic reduction (on Pd-C) of the triazines afforded their 2,5-dihydro compounds.