7726-45-6

Basic information

• Product Name: 5-PHENYL-PENTANENITRILE
• Synonyms: 5-PHENYL-PENTANENITRILE
• CAS NO: 7726-45-6
• Molecular Formula: C₁₁H₁₃N
• Molecular Weight: 159.22762
• Mol File: 7726-45-6.mol
• Article Data: 31

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-PHENYL-PENTANENITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-PHENYL-PENTANENITRILE(7726-45-6)
• EPA Substance Registry System: 5-PHENYL-PENTANENITRILE(7726-45-6)

Safety Data

• Hazardous Substances Data: 7726-45-6(Hazardous Substances Data)

Upstream product

• 15295-69-9 hept-6-ynenitrile 
• 74-86-2 acetylene 
• 591-50-4 iodobenzene 
• 5414-21-1 5-bromopentan-1-nitrile 
• 100-47-0 benzonitrile 
• 60-12-8 2-phenylethanol 
• 107-13-1 acrylonitrile 
• 824-90-8 1-phenylbut-1-ene 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 557-21-1 zinc(II) cyanide 
• 2489-87-4 2-allylnaphthalene 
• 14371-10-9 (E)-3-phenylpropenal 
• 16640-68-9 cyanomethylene triphenylphosphorane 
• 108-86-1 bromobenzene 

Downstream Products

• 2270-20-4 5-Phenylpentanoic acid 
• 1430423-74-7 5-fluoro-5-phenylpentanenitrile 
• 17734-21-3 5-phenylpentylamine 
• 1407999-29-4 C₁₇H₂₃N₃O₄ 
• 10413-00-0 5-oxo-5-phenylpentanenitrile 
• 1373439-91-8 C₁₁H₁₀BrNO 
• 1332887-21-4 4-cyano-1-phenylbutyl nitrate 
• 104-51-8 1-butylbenzene 
• 84831-70-9 [2,5-Dimethyl-4-(3-phenyl-propyl)-2H-pyrazol-3-yl]-urea 
• 84831-62-9 5-Isocyanato-1,3-dimethyl-4-(3-phenyl-propyl)-1H-pyrazole 
• 84831-57-2 2,5-Dimethyl-4-(3-phenyl-propyl)-2H-pyrazol-3-ylamine 
• 84831-53-8 2-Acetyl-5-phenyl-pentanenitrile 
• 36884-28-3 5-phenyl-1-pentanal 

Relevant articles and documents

Synthesis of gem-Difluoroalkenes by Merging Ni-Catalyzed C-F and C-C Bond Activation in Cross-Electrophile Coupling

By merging C-F and C-C bond activation in the cross-electrophile coupling, we developed an efficient cyanide-free synthesis of diverse functional-group-rich cyano-substituted gem-difluoroalkenes using cyclobutanone oxime esters and trifluoromethyl alkenes

Ni-Catalyzed Isomerization-Hydrocyanation Tandem Reactions: Access to Linear Nitriles from Aliphatic Internal Olefins

A highly regioselective nickel-based catalyst system for the isomerization/hydrocyanation of aliphatic internal olefins is described. This benign tandem reaction provides facile access to a wide variety of aliphatic nitriles in good yields with excellent regioselectivities. Thanks to Lewis acid-free conditions, the protocol features board functional groups tolerance, including secondary amine and unprotected alcohol groups.

One-Pot, Tandem Wittig Hydrogenation: Formal C(sp3)-C(sp3) Bond Formation with Extensive Scope

A one-pot, tandem Wittig hydrogenation of aldehydes with stabilized ylides is reported, representing a formal C(sp3)-C(sp3) bond construction. The tandem reaction operates under mild conditions, is high yielding, and is broad in scope. Chemoselectivity for olefin reduction is observed, and the methodology is demonstrated in the synthesis of lapatinib analogues and a formal synthesis of (±)-cuspareine. Early insights suggest that the chemoselectivity observed in the reduction step is due to partial poisoning of the catalyst, after step one, thus adding to the power of the one-pot procedure.