77347-19-4

Basic information

• Product Name: (2-hydroxy-5-methylbenzene-1,3-diyl)bis(phenylmethanone)
• Synonyms: methanone, 1,1'-(2-hydroxy-5-methyl-1,3-phenylene)bis[1-phenyl-
• CAS NO: 77347-19-4
• Molecular Formula: C₂₁H₁₆O₃
• Molecular Weight: 316.3499
• Mol File: 77347-19-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 477°C at 760 mmHg
• Flash Point: 256.4°C
• Density: 1.215g/cm³
• Vapor Pressure: 1.01E-09mmHg at 25°C
• Refractive Index: 1.629
• CAS DataBase Reference: (2-hydroxy-5-methylbenzene-1,3-diyl)bis(phenylmethanone)(CAS DataBase Reference)
• NIST Chemistry Reference: (2-hydroxy-5-methylbenzene-1,3-diyl)bis(phenylmethanone)(77347-19-4)
• EPA Substance Registry System: (2-hydroxy-5-methylbenzene-1,3-diyl)bis(phenylmethanone)(77347-19-4)

Safety Data

• Hazardous Substances Data: 77347-19-4(Hazardous Substances Data)

Usage

General Description

(2-hydroxy-5-methylbenzene-1,3-diyl)bis(phenylmethanone), also known as bis(4-hydroxy-3-methylphenyl)methanone, is a chemical compound primarily used as a photoinitiator in the polymer industry. It is a pale yellow solid that is soluble in organic solvents such as acetone, toluene, and ethyl acetate. (2-hydroxy-5-methylbenzene-1,3-diyl)bis(phenylmethanone) is commonly used in the production of UV-curable coatings, inks, and adhesives, as it absorbs UV light and initiates the crosslinking of polymers. It is also utilized as a stabilizer in the photopolymerization of dental restorative materials. Additionally, it has potential applications in the pharmaceutical and cosmetic industries for its antioxidant and photoprotective properties. However, it is important to handle this compound with caution and adhere to proper safety protocols due to its potential health and environmental hazards.

Upstream product

• 106-44-5 p-cresol 
• 98-07-7 Benzotrichlorid 
• 1470-57-1 2-hydroxy-5-methylbenzophenone 
• 98-88-4 benzoyl chloride 
• 611-73-4 Benzoylformic acid 
• 5720-05-8 4-methylphenylboronic acid 
• 220464-86-8 N-(4-methylphenoxy)phthalimide 
• 65440-81-5 O-(4-methylphenyl)hydroxylamine 
• 7310-95-4 2-Hydroxy-5-methylisophthalaldehyde 
• 98-80-6 phenylboronic acid 
• 344563-86-6 2-benzoyl-4-methylphenyl benzoate 

Downstream Products

• 363594-09-6 Cl₂Fe((C₆H₄NC(C₆H₅)C₆H₂(OH)(CH₃)C(C₆H₅)N)2)⁽¹⁺⁾*Cl^(1-)=[Fe((C₆H₄NC(C₆H₅)C₆H₂(OH)(CH₃)C(C₆H₅)N)2)Cl₂]Cl 
• 1032650-77-3 2-[N-(3-amonopropyl)benzimidoyl]-6-benzoyl-4-methylphenol 
• 1261216-10-7 2,6-bis({N-[2-(phenyltelluro)ethyl]}benzimidoyl)-4-methylphenol 
• 1261216-11-8 2,6-bis({N-[3-(phenyltelluro)propyl]}benzimidoyl)-4-methylphenol 

Relevant articles and documents

RhIII-Catalyzed Decarboxylative o-Acylation of Arenes Bearing an Oxidizing Directing Group

Here in we report, rhodium(III)-catalyzed decarboxylative acylation of arenes using α-oxocarboxylic acids as acyl surrogate. In this strategy, O–NHAc group act as an autocleavable oxidizing directing group (ODGauto), thus giving rise to ortho-acylated phenols in moderate to good yields. Mechanistic studies provided strong support for a kinetically relevant C–H bond activation. According to the best of our knowledge, this is the first report of Rhodium catalyzed decarboxylative acylation.

Synthesis of some newer analogues of substituted dibenzoyl phenol as potent anti-inflammatory agents

The newly synthesized compounds dibenzoyl phenols 4a-f using microwave irradiation were screened for their anti-inflammatory activity and compared with standard drugs. Benzoylation of hydroxybenzophenones 1a-f affords substituted benzoyl phenyl benzoates

Dinuclear Metal Complexes. Part 2. Synthesis, Characterisation, and Electrochemical Studies of Macrocyclic Dicopper(II) Complexes

The synthesis, characterisation, and electrochemical studies of dicopper(II) complexes 1>2.nH2O of the macrocycle 7,11;19,23-dimetheno-9,21-dimethyl-tetra-azacycloicosa-5,7,9,12,17,19,21,24-octaene-25,26-diol (H2L1), and of some 6,12,18,24-substituted (Me4; Prn4; Ph4; Ph, Me, Ph, Me) derivatives have been carried out.These compounds undergo sequential one-electron transfers at two different potentials.For all of these compounds, except for 1>2.2H2O, two reversible or almost reversible reduction steps have been observed in acetonitrile medium using a hanging mercury drop electrode.In the case of 1>2.2H2O, the second couple became obscured due to the presence of an adsorption phenomenon or secondary electrode reaction.However, in NN-dimethylformamide (dmf) medium, satisfactory voltammograms have been obtained only with 1>2.2H2O.The mixed-valent complexes are considerably more stable in acetonitrile than is IICuIL1>+ in dmf.The potentials of the first reduction step (E1) remain practically invariant throughout the series and are independent of the extent of magnetic interactions in the dicopper(II) complexes.The potentials of the second reduction step (E2) vary with the alkyl and aryl groups present, and a linear plot has been obtained for E2 vs. the Hammett function ?m.On the basis of previously reported observations and the present study it is inferred that in acetonitrile medium the unpaired electron in the mixed-valent complexes remains localised on one of the copper atoms.