77363-90-7Relevant academic research and scientific papers
Synthesis of functionalized tetrahydrofurans
Semple, J.Edward,Guthrie, Anne E.,Joullie, Madeleine M.
, p. 4561 - 4564 (1980)
A novel cyclization reaction is described which affords readily manipulable 3(2H)-dihydrofuranone ethylene ketals, useful in the total synthesis of an ascofuranone model, bullatenone, and muscarine analogs.
KINETIC RESOLUTION OF CHIRAL AMINES
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Page/Page column 126; 127, (2013/03/26)
The present invention refers to a method for the kinetic resolution of a chiral primary or secondary amine by treating the amine with a chiral, hydroxamic acid derived reagent of the formula (I). These chiral reagents are particularly useful for the kinetic resolution of cyclic amines and may be generated in situ in the presence of an N-heterocyclic carbene, thus allowing for a catalytic reaction.
