774-44-7

Basic information

• Product Name: 4-methyl-2-phenyl-1,3-dioxane
• Synonyms: 4-methyl-2-phenyl-1,3-dioxane
• CAS NO: 774-44-7
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.22766
• EINECS: 212-264-6
• Mol File: 774-44-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 266.1°C at 760 mmHg
• Flash Point: 119°C
• Appearance: /
• Density: 1.031g/cm³
• Vapor Pressure: 0.0145mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: 4-methyl-2-phenyl-1,3-dioxane(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-2-phenyl-1,3-dioxane(774-44-7)
• EPA Substance Registry System: 4-methyl-2-phenyl-1,3-dioxane(774-44-7)

Safety Data

• Hazardous Substances Data: 774-44-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14O2/c1-9-7-8-12-11(13-9)10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3

Upstream product

• 18826-95-4 1.3-butanediol 
• 100-52-7 benzaldehyde 
• 6296-95-3 1,1,2-triphenyl-1,2-ethanediol 
• 579-43-1 (1S,2R)-1,2-diphenylethane-1,2-diol 
• 1439-07-2 trans-Stilbene oxide 

Downstream Products

• 136367-86-7 C₂₄H₃₀O₂ 
• 59694-08-5 3-hydroxylbutyl benzoate 
• 80403-62-9 4-hydroxybut-2-yl benzoate 
• 2867-66-5 1-benzoyloxy-3-bromobutane 
• 51591-50-5 3-benzoyloxy-1-bromobutane 
• 136-60-7 benzoic acid, butyl ester 
• 4909-81-3 s-butyl benzoate 
• 52657-84-8 (±)-3-benzyloxybutan-1-ol 
• 90458-77-8 3-(benzyloxy)butanal 
• 4799-69-3 4-benzyloxy-2-butanol 
• 167163-46-4 C₁₁H₁₂O₄ 
• 104311-81-1 4-benzoyloxypentanenitrile 
• 54889-80-4 1,3-dibenzyloxybutane 
• 65-85-0 benzoic acid 

Relevant articles and documents

Macro-cyclic immuno-modulator

The invention provides a macro-cyclic immuno-modulator, and discloses a compound shown as a formula I, and a tautomer, an enantiomer, a pharmaceutically acceptable salt, a crystal form, hydrate or solvate thereof. Experiment results show that the compound can be effectively combined with STING and has a good STING protein excitation function. Therefore, the compound can be used as an STING agonist, can be used to treat various related diseases, and has a very good application prospect in preparing medicines for treating diseases related to STING activity, especially medicines for treating inflammatory and autoimmune diseases, infectious diseases, cancers or precancerous syndromes.

Chemoselective conversion of aromatic epoxide and 1,2-diol to 1,3-dioxane derivatives with phenyltrimethylammonium tribromide in the presence of a catalytic amount of antimony(III) bromide

trans-Stilbene oxide was oxidatively converted to 2-phenyl-1,3-dioxanes with phenyltrimethylammonium tribromide in the presence of various 1,3-diols and a catalytic amount of SbBr3 in DMSO at room temperature. Aromatic 1,2-diol, such as hydrobenzoin, was similarly converted to 2-aryl-1,3-dioxane derivatives under the same reaction conditions.

2,4,4,6-Tetrabromo-2,5-cyclohexadienone (TABCO) as a versatile, efficient, and chemoselective catalyst for the acetalization and transacetalization of carbonyl compounds, the preparation of acetonides from epoxides and acylals (1,1-diacetates) from aldehydes

The efficient and chemoselective preparation of acetals and ketals from carbonyl compounds, transacetalization reactions, the conversion of epoxides to acetonides, and the preparation of acylals from aldehydes in the presence of catalytic amounts of 2,4,4,6-tetrabromo-2,5-cyclohexadienone (TABCO) are described.