77435-42-8 Usage
Uses
Used in Medicinal Chemistry and Drug Discovery:
1H-Pyrazole-4-carboxylic acid, 1,3-dimethyl-5-phenyl-, ethyl ester is utilized as a building block for the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a valuable component in the development of new drugs with potential therapeutic benefits.
Used in Agrochemicals Production:
1H-Pyrazole-4-carboxylic acid, 1,3-dimethyl-5-phenyl-, ethyl ester also serves as a key intermediate in the production of certain agrochemicals, contributing to the development of effective solutions for agricultural applications.
Used in Specialty Chemicals Production:
1H-Pyrazole-4-carboxylic acid, 1,3-dimethyl-5-phenyl-, ethyl ester is employed in the synthesis of specialty chemicals, where its specific properties can be leveraged to create high-value products for various industries.
Used in Research and Development:
Due to its potential biological activities, 1H-Pyrazole-4-carboxylic acid, 1,3-dimethyl-5-phenyl-, ethyl ester is of interest to researchers who are exploring its possible therapeutic applications and furthering the understanding of its properties and interactions within biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 77435-42-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,4,3 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 77435-42:
(7*7)+(6*7)+(5*4)+(4*3)+(3*5)+(2*4)+(1*2)=148
148 % 10 = 8
So 77435-42-8 is a valid CAS Registry Number.
77435-42-8Relevant academic research and scientific papers
CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF
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, (2018/04/17)
Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.
PYRAZOLE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS
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Paragraph 0133; 0134; 0135; 0136, (2017/09/02)
Compounds of formula (I) defined herein are phosphoinositide 3-kinases (PI3K) inhibitors and are useful for the treatment of disorders associated with PI3K enzymes.
Decarboxylative Fluorination of Electron-Rich Heteroaromatic Carboxylic Acids with Selectfluor
Yuan, Xi,Yao, Jian-Fei,Tang, Zhen-Yu
, p. 1410 - 1413 (2017/03/23)
A transition-metal-free decarboxylative fluorination of electron-rich five-membered heteroaromatics, including furan-, pyrazole-, isoxazole-, thiophene-, indole-, benzofuran- and indazolecarboxylic acids, with Selectfluor is reported. Fluorinated dimer products were observed for nitrogen-containing heteroaromatic carboxylic acids, such as indole and pyrazole. An effective method has been developed to synthesize the monomer of 2- and 3-fluoroindoles with Li2CO3 as base at low temperature.
Synthesis of 4-Acyl- and 4-Alkoxy-carbonylpyrazoles
Al-Saleh, Fowzia S.,Khawaja, Ibtisam K. Al,Joule, John A.
, p. 642 - 645 (2007/10/02)
N'-Aroyl- or N'-acetyl, N'-phenyl- or N'-methyl-hydrazino-derivatives (1) of 1,3-dicarbonyl compounds can be converted by mild base treatment into 5-aryl- or 5-methyl-, 1-phenyl- or 1-methylpyrazoles carrying an acyl or alkoxycarbonyl group at C-4.
