77435-42-8

Basic information

• Product Name: 1H-Pyrazole-4-carboxylic acid, 1,3-dimethyl-5-phenyl-, ethyl ester
• CAS NO: 77435-42-8
• Molecular Formula: C14H16N2O2
• Molecular Weight: 244.293
• Mol File: 77435-42-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole-4-carboxylic acid, 1,3-dimethyl-5-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-4-carboxylic acid, 1,3-dimethyl-5-phenyl-, ethyl ester(77435-42-8)
• EPA Substance Registry System: 1H-Pyrazole-4-carboxylic acid, 1,3-dimethyl-5-phenyl-, ethyl ester(77435-42-8)

Safety Data

• Hazardous Substances Data: 77435-42-8(Hazardous Substances Data)

Usage

General Description

1H-Pyrazole-4-carboxylic acid, 1,3-dimethyl-5-phenyl-, ethyl ester is a chemical compound with the molecular formula C15H16N2O2. It is an ethyl ester derivative of 1H-pyrazole-4-carboxylic acid that contains two methyl groups and a phenyl group. 1H-Pyrazole-4-carboxylic acid, 1,3-dimethyl-5-phenyl-, ethyl ester is commonly used in the field of medicinal chemistry and drug discovery as a building block for the synthesis of various pharmaceutical compounds. It is also a key intermediate in the production of certain agrochemicals and specialty chemicals. The compound is known for its potential biological activities and is of interest to researchers for its potential therapeutic applications.

Upstream product

• 1483-24-5 1-methyl-1-benzoylhydrazine 
• 141-97-9 ethyl acetoacetate 
• 76923-16-5 ethyl 3-methyl-5-phenyl-1H-pyrazole-4-carboxylate 
• 74-88-4 methyl iodide 
• 569-37-9 ethyl 3-oxo-2-benzoylbutanoate 
• 98-88-4 benzoyl chloride 

Downstream Products

• 861586-02-9 1,3-dimethyl-5-phenyl-1H-pyrazole-4-carboxylic acid 
• 1318239-50-7 4-fluoro-1,3-dimethyl-5-phenyl-1H-pyrazole 

Relevant articles and documents

CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.

Decarboxylative Fluorination of Electron-Rich Heteroaromatic Carboxylic Acids with Selectfluor

A transition-metal-free decarboxylative fluorination of electron-rich five-membered heteroaromatics, including furan-, pyrazole-, isoxazole-, thiophene-, indole-, benzofuran- and indazolecarboxylic acids, with Selectfluor is reported. Fluorinated dimer products were observed for nitrogen-containing heteroaromatic carboxylic acids, such as indole and pyrazole. An effective method has been developed to synthesize the monomer of 2- and 3-fluoroindoles with Li2CO3 as base at low temperature.