569-37-9Relevant articles and documents
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Shriner,Schmidt,Roll
, p. 33; Coll. Vol. II <1943>, 266 (1938)
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Benzoyl acid ethyl ester preparation method (by machine translation)
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Paragraph 0007; 0034-0053, (2018/05/01)
A benzoyl acid ethyl ester preparation method, characterized in that comprises the following steps: step (1): in the non-proton solvent, adding a weak inorganic base, slowly adding acetyl ethyl acetate, then dropwise benzoyl chloride reaction; step (2): add the strong inorganic base to carry out the reaction, after the reaction, filtration, shall be benzoyl ethyl acetate, the filtrate is distilled, the recovered solvent is recycled; wherein in the in the whole reaction process, does not add the aqueous reagent. The method of the whole in the preparation of waste water and gas produced, only a small amount of residue are produced, and environmental protection. Prepared by the method of the benzoyl ethyl acetate purity>94%, yield>99%, and the equipment requirement is low, and is suitable for large-scale industrial production. (by machine translation)
Decarboxylative Fluorination of Electron-Rich Heteroaromatic Carboxylic Acids with Selectfluor
Yuan, Xi,Yao, Jian-Fei,Tang, Zhen-Yu
supporting information, p. 1410 - 1413 (2017/03/23)
A transition-metal-free decarboxylative fluorination of electron-rich five-membered heteroaromatics, including furan-, pyrazole-, isoxazole-, thiophene-, indole-, benzofuran- and indazolecarboxylic acids, with Selectfluor is reported. Fluorinated dimer products were observed for nitrogen-containing heteroaromatic carboxylic acids, such as indole and pyrazole. An effective method has been developed to synthesize the monomer of 2- and 3-fluoroindoles with Li2CO3 as base at low temperature.