775-27-9

Basic information

• Product Name: 4-methoxyphenyl sulfurofluoridate
• Synonyms: 4-methoxyphenyl sulfurofluoridate
• CAS NO: 775-27-9
• Molecular Weight: 206.195
• Mol File: 775-27-9.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 4-methoxyphenyl sulfurofluoridate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxyphenyl sulfurofluoridate(775-27-9)
• EPA Substance Registry System: 4-methoxyphenyl sulfurofluoridate(775-27-9)

Safety Data

• Hazardous Substances Data: 775-27-9(Hazardous Substances Data)

Upstream product

• 1139705-25-1 4-methoxyphenyl 1H-imidazole-1-sulfonate 
• 640723-20-2 fluorosulfonyl fluoride 
• 150-76-5 4-methoxy-phenol 

Downstream Products

• 94-30-4 ethyl 4-methoxybenzoate 
• 100-09-4 4-methoxybenzoic acid 
• 53040-92-9 4-(4-tolyl)anisole 
• 17171-17-4 4'-methoxy-3-methylbiphenyl 
• 874-90-8 4-methoxybenzonitrile 
• 459-60-9 1-fluoro-4-methoxybenzene 
• 146857-78-5 (Z)-1-methoxy-4-(oct-1-en-1-yl)benzene 
• 129182-23-6 1-methoxy-4-(oct-1-en-2-yl)benzene 
• 4333-75-9 1-(4-methoxyphenyl)-1-phenylethene 
• 1694-19-5 p-methoxystilbene 
• 1208-86-2 N-(4-methoxyphenyl)phenylamine 
• 613-37-6 4-methoxylbiphenyl 
• 637-69-4 4-Methoxystyrene 
• 121-98-2 methyl 4-methoxybenzoate 

Relevant articles and documents

Nickel- and Palladium-Catalyzed Cross-Coupling of Aryl Fluorosulfonates and Phosphites: Synthesis of Aryl Phosphonates

The synthesis of aryl phosphonates via nickel and palladium-catalyzed cross-coupling of aryl fluorosulfonates and phosphites is described. The products were obtained in good to excellent yields under mild conditions with broad functional group compatibility, employing either Pd(OAc)2 and DPEPhos or the readily available NiCl2(dme) and Xantphos as catalytic systems. Noteworthily, the present C(sp2)?P bond formation method could be applied to the direct conversion of phenols to the corresponding aryl phosphonates in one pot via reaction of phenols with SO2F2 and subsequent palladium-catalyzed cross-coupling.

NiCl 2as a Cheap and Efficient Precatalyst for the Coupling of Aryl Fluorosulfonate and Phosphite/Phosphine Oxide

Herein, NiCl 2is employed as a cheap precatalyst in the formation of C(sp 2)-P bond via cross-coupling reaction of phenol derivatives and phosphine oxides/phosphites. This catalytic system allows a variety of phenols with diverse functional groups to transform into phosphates with good yields. No additional additive is used in this reaction.

Continuous flow synthesis of aryl aldehydes by Pd-catalyzed formylation of phenol-derived aryl fluorosulfonates using syngas

This communication describes the palladium-catalyzed reductive carbonylation of aryl fluorosulfonates (ArOSO2F) using syngas as an inexpensive and sustainable source of carbon monoxide and hydrogen. The conversion of phenols to aryl fluorosulfonates can be conveniently achieved by employing the inexpensive commodity chemical sulfuryl fluoride (SO2F2) and base. The developed continuous flow formylation protocol requires relatively low loadings for palladium acetate (1.25 mol%) and ligand (2.5 mol%). Good to excellent yields of aryl aldehydes were obtained within 45 min for substrates containing electron withdrawing substituents, and 2 h for substrates containing electron donating substituents. The optimal reaction conditions were identified as 120 °C temperature and 20 bar pressure in dimethyl sulfoxide (DMSO) as solvent. DMSO was crucial in suppressing Pd black formation and enhancing reaction rate and selectivity. This journal is