7753-73-3Relevant academic research and scientific papers
Differentially-protected steroidal triamines; scaffolds with potential for medicinal, supramolecular, and combinatorial chemistry
Amo, Vicente Del,Siracusa, Laura,Markidis, Theodoros,Baragana, Beatriz,Bhattarai, Khadga M.,Galobardes, Marta,Naredo, Gregorio,Perez-Payan, M. Nieves,Davis, Anthony P.
, p. 3320 - 3328 (2007/10/03)
Cholic acid 2a has been converted into two new orthogonally-protected triamino scaffolds, 13 and 14. The synthesis proceeds via the bis-Boc-NH-substituted azide 10, for which an improved preparation is described. After removal of the Boc groups, the two a
The 'triamino-analogue' of methyl cholate; a practical, large-scale synthesis
Davis, Anthony P.,Pérez-Payán, M. Nieves
, p. 991 - 993 (2007/10/03)
The triamino steroids 2 are in demand as facial amphiphiles and starting materials for supramolecular chemistry. 2 (R = Me)is now available from cholic acid 1 in substantial quantities via a new, high-yielding procedure.
