77603-45-3

Basic information

• Product Name: 6-BROMOISATIN
• Synonyms: 6-BROMOINDOLE-2,3-DIONE;6-BROMOINDOLINE-2,3-DIONE;6-BROMO ISATINIC ANHYDRIDE;AKOS B018432;BUTTPARK 50\07-95;BROMOISATIN(6-);5-Bromo-2H-3,1-benzoxazine-2,4(1H)-dione;2H-3,1-Benzoxazine-2,4(1H)-dione, 5-broMo-
• CAS NO: 77603-45-3
• Molecular Formula: C₈H₄BrNO₃
• Molecular Weight: 226.03
• Mol File: 77603-45-3.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Density: 1.826
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 6-BROMOISATIN(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMOISATIN(77603-45-3)
• EPA Substance Registry System: 6-BROMOISATIN(77603-45-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 77603-45-3(Hazardous Substances Data)

Usage

General Description

6-Bromoisatin, also known as 2-bromoindole-3-carboxaldehyde, is a chemical compound with the molecular formula C8H6BrNO. It is a brominated derivative of isatin, a naturally occurring compound found in various plants. 6-Bromoisatin has been studied for its potential pharmacological properties, including its anti-cancer and anti-inflammatory activities. It has also been investigated for its use in the synthesis of pharmaceutical drugs and organic compounds. Additionally, 6-Bromoisatin has been explored for its potential as a fluorescent probe in biological and cellular imaging studies. Overall, 6-Bromoisatin is a versatile and important chemical compound with various potential applications in the fields of medicine, pharmacology, and chemical synthesis.

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Relevant articles and documents

QUINAZOLINONE HSD17B13 INHIBITORS AND USES THEREOF

Described herein are HSD17B13 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of liver disease, metabolic disease, or cardiovascular disease, such as NAFLD or NASH,

Recyclable (PhSe)2-catalyzed selective oxidation of isatin by H2O2: a practical and waste-free access to isatoic anhydride under mild and neutral conditions

After a series of careful conditional optimizations and catalyst screenings, a methodology to prepare isatoic anhydrides through organoselenium-catalyzed selective oxidation of isatins by H2O2 under mild and neutral conditions was developed. The reactions were very practical because of the recyclability of the catalyst and solvent and the convenient isolation procedures of the products. This work reports the organoselenium-catalyzed oxidation of heterocycles that greatly expands the application scopes of organoselenium catalysis. It also indicates that the organoselenium catalysts are robust enough to be recycled in industrial production if suitable isolation procedures are developed.

Is the 2,3-carbon-carbon bond of indole really inert to oxidative cleavage by Oxone?-Synthesis of isatoic anhydrides from indoles

A recent report has indicated that the oxidizing agent Oxone does not possess the ability to cleave the 2,3-carbon-carbon bond of indole. Work in our laboratory shows that this is not the case. Indole and a variety of aryl ring substituted derivatives readily react to form synthetically important isatoic anhydrides.