77614-31-4

Upstream product

• 77614-30-3 (R)-(+)-3-(4-methyl-3-cyclohexen-1-yl)-3-buten-1-ol 
• 67-64-1 acetone 
• 5989-27-5 D-limonene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 262290-97-1 (1R)-5-[(1S)-3-Hydroxy-1,5-dimethylhexyl]-2-methylenecyclohexanol 
• 262290-96-0 (2S)-2-[(1R)-4-Methylcyclohex-3-enyl]-6-methylheptan-4-ol 
• 262290-92-6 (S)-3-((R)-4-Methyl-cyclohex-3-enyl)-butan-1-ol 
• 128300-30-1 (S)-3-((R)-4-methylcyclohex-3-en-1-yl)butanal 
• 26575-87-1 (+)-epijuvabione 
• 26091-09-8 (+)-Epitodomatuic acid 
• 26462-78-2 (R)-4-((S)-1,5-Dimethyl-3-oxo-hexyl)-cyclohex-1-enecarbaldehyde 
• 77647-35-9 (1'R)-(2Z)-3-methyl-3-(4'-methylcyclohexene-3'-yl)-propen-2-al-1 
• 73088-68-3 (1'R)-(2E)-3-methyl-3-(4'-methylcyclohexen-3'-yl)-propen-2-al-1 

Relevant academic research and scientific papers

Baker's yeast mediated enantioselective synthesis of the bisabolene sesquiterpenes (+)-epijuvabione and (-)-juvabione

Fermenting baker's yeast converts the unsaturated aldehydes 7 and 11 into the saturated alcohols 8 and 12, respectively. The microbial saturation of the double bond proceeds in high chemical yields and the stereoselectivity of the reduction is strongly influenced by the E:Z ratio of the substrate. Enantiopure 8 and 12 are chiral building blocks for the synthesis of bisabolene sesquiterpenes and their usefulness is shown in the preparation of (+)-epijuvabione 1 and (-)-juvabione 3.

INSECT GROWTH REGULATORS-VIII. SYNTHESIS OF A CYCLIC ANALOG OF JUVENILE HORMONE-II

The "true" cyclic analog of JH-II was obtained in a six step synthesis from natural (+)-limonene as starting material.