26462-78-2

Upstream product

• 58475-12-0 4-[(R)-4-(5,5-Dimethyl-[1,3]dioxan-2-yl)-cyclohex-3-enyl]-2-isobutyl-2-methylsulfanyl-pentanoic acid 
• 26462-77-1 (S)-2-Methyl-6-((R)-4-methyl-cyclohex-3-enyl)-heptan-4-one 
• 262290-97-1 (1R)-5-[(1S)-3-Hydroxy-1,5-dimethylhexyl]-2-methylenecyclohexanol 
• 5989-27-5 D-limonene 
• 13835-75-1 (2R)-2-[(1R)-4-methylcyclohex-3-en-1-yl]propan-1-ol 
• 13835-32-0 (2R)-2-[(1R)-4-methylcyclohex-3-en-1-yl]propyl 3,5-dinitrobenzoate 
• 26462-76-0 (S)-3-((R)-4-methylcyclohex-3-en-1-yl)butanenitrile 
• 26462-75-9 Toluene-4-sulfonic acid (R)-2-((R)-4-methyl-cyclohex-3-enyl)-propyl ester 
• 262290-94-8 (3S)-3-[(1R)-4-Methylcyclohex-3-enyl]butanol dinitrobenzoate ester 
• 262290-96-0 (2S)-2-[(1R)-4-Methylcyclohex-3-enyl]-6-methylheptan-4-ol 
• 262290-92-6 (S)-3-((R)-4-Methyl-cyclohex-3-enyl)-butan-1-ol 
• 73088-68-3 (1'R)-(2E)-3-methyl-3-(4'-methylcyclohexen-3'-yl)-propen-2-al-1 
• 15760-18-6 9-Hydroxy-methyl-Δ¹-p-menthen 
• 128300-30-1 (S)-3-((R)-4-methylcyclohex-3-en-1-yl)butanal 

Downstream Products

• 26091-09-8 (+)-Epitodomatuic acid 
• 26575-87-1 (+)-epijuvabione 
• 16981-74-1 Juvabion 

Relevant academic research and scientific papers

Baker's yeast mediated enantioselective synthesis of the bisabolene sesquiterpenes (+)-epijuvabione and (-)-juvabione

Fermenting baker's yeast converts the unsaturated aldehydes 7 and 11 into the saturated alcohols 8 and 12, respectively. The microbial saturation of the double bond proceeds in high chemical yields and the stereoselectivity of the reduction is strongly influenced by the E:Z ratio of the substrate. Enantiopure 8 and 12 are chiral building blocks for the synthesis of bisabolene sesquiterpenes and their usefulness is shown in the preparation of (+)-epijuvabione 1 and (-)-juvabione 3.