77635-19-9Relevant academic research and scientific papers
Facile one-pot transformation of phenols into o-cyanophenols
Nakai, Yuhta,Moriyama, Katsuhiko,Togo, Hideo
, p. 6077 - 6083 (2015/03/30)
The treatment of phenols with paraformaldehyde in the presence of MgCl2 and Et3N in THF at 80 C, followed by reaction with molecular iodine and aq. ammonia at room temperature provided the corresponding o-cyanophenols in moderate to good yields. The present reaction is a one-pot transformation of phenols into o-cyanophenols using much less expensive reagents than are typically used; the reaction is free of both transition-metals and cyanide. The utility of this reaction was highlighted during our preparation of Febuxostat from p-bromophenol.
Uniform porous nanospheres of discrete shape-persistent organic cage compounds
Schneider, Markus W.,Lechner, Lorenz G.,Mastalerz, Michael
supporting information; experimental part, p. 7113 - 7116 (2012/05/20)
By mixing solutions of the reactants for shape-persistent cage compounds in a binary solvent mixture, spheres in the nanometre regime with controlled sizes can be generated, which show permanent porosities.
B-Alkyl Suzuki-Miyaura cross-coupling of tri-n-alkylboranes with arylbromides bearing acidic functions under mild non-aqueous conditions
Sun, Hui-Xia,Sun, Zhi-Hua,Wang, Bing
experimental part, p. 1596 - 1599 (2009/06/18)
An efficient and chemoselective Pd-catalyzed B-alkyl Suzuki-Miyaura cross-coupling of tri-n-alkylboranes with arylbromides possessing acidic functions is described. This protocol features the relatively weak base Cs2CO3 and mild non-
Direct B-alkyl Suzuki-Miyaura cross-coupling of trialkyl-boranes with aryl bromides in the presence of unmasked acidic or basic functions and base-labile protections under mild non-aqueous conditions
Wang, Bing,Sun, Hui-Xia,Sun, Zhi-Hua,Lin, Guo-Qiang
experimental part, p. 415 - 422 (2009/10/23)
An efficient and chemoselective palladium-catalyzed direct B-alkyl Suzuki-Miyaura cross-coupling of trialkylboranes with diversely functionalized aryl bromides is described. A wide variety of unmasked acidic or basic functions are tolerated. The mild non-
Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins
-
, (2008/06/13)
The invention relates to a method for producing special transition metal compounds, to novel transition metal compounds and to the use of the same for the polymerisation of olefins.
Selectivity in the photodimerization of 6-alkylcoumarins
Yu, Xiuling,Scheller, Dieter,Rademacher, Otto,Wolff, Thomas
, p. 7386 - 7399 (2007/10/03)
Coumarin and 6-alkylcoumarins (alkyl = C1 to C16) were photodimerized in homogeneous solvents differing in polarity and in aqueous micellar solutions. The four possible photodimers, syn head-to-head (hh), anti head-to-head, syn head-to-tail (ht), and anti head-to-tail, were identified through a combination of X-ray analysis and NMR spectroscopy. In 6-methylcoumarin the concentration-corrected dimerization (quantum) yield increases with decreasing concentration of the educt; anti- hh was formed exclusively in nonpolar solvents and upon triplet sensitization and was the main product under all conditions except for ionic micellar systems, which direct to preferred syn-hh dimerization. Long alkyl substituents, however, lead to anti-hh in polar solvents and in micelles, too. Predominating ht dimer formation was observed for nonsubstituted coumarin in polar solvents only. Thus, syn/anti and hh/ht selectivity can be steered by varying the 6-alkyl substituent. Syn- hh photodimers of 6-methylcoumarin can be photochemically split into the monomers; they partly proved thermally unstable against acids, bases, methanol, and on SiO2 surfaces.
