77651-69-5

Basic information

• Product Name: 2-phenyl-3-(2-methylpropyl)-4(3H)-quinazolinone
• CAS NO: 77651-69-5
• Molecular Weight: 278.354
• Mol File: 77651-69-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-phenyl-3-(2-methylpropyl)-4(3H)-quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-3-(2-methylpropyl)-4(3H)-quinazolinone(77651-69-5)
• EPA Substance Registry System: 2-phenyl-3-(2-methylpropyl)-4(3H)-quinazolinone(77651-69-5)

Safety Data

• Hazardous Substances Data: 77651-69-5(Hazardous Substances Data)

Upstream product

• 134-20-3 2-carbomethoxyaniline 
• 98-88-4 benzoyl chloride 
• 5041-09-8 isobutylamine hydrochloride 
• 7510-49-8 methyl 2-(benzamido)benzoate 

Relevant articles and documents

Phosphoramides. XIII. Phosphorus Pentaoxide-Amine Hydrochloride Mixtures as Reagents in the Synthesis of 4(3H)-Quinazolinones and 4-Quinazolinamines

4(3H)-Quinazolinones 3a-r have been prepared by heating methyl N-acylanthranilates 1a-c and the hydrochlorides of primary aliphatic and aromatic amines with phosphorus pentaoxide and N,N-dimethylcyclohexylamine at 180 deg C. 4-Quinazolinamines 4 and the amidine 7 were isolated as by-products.The carboxamides 5 and 6 were believed to be reaction intermediates.By raising the temperature to 250 deg C 4 was obtained in a preparative yield.