77651-73-1

Basic information

• Product Name: 2-phenyl-N-propyl-4-quinazolinamine
• Synonyms: 2-phenyl-N-propyl-4-quinazolinamine
• CAS NO: 77651-73-1
• Molecular Weight: 263.342
• Mol File: 77651-73-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-phenyl-N-propyl-4-quinazolinamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-N-propyl-4-quinazolinamine(77651-73-1)
• EPA Substance Registry System: 2-phenyl-N-propyl-4-quinazolinamine(77651-73-1)

Safety Data

• Hazardous Substances Data: 77651-73-1(Hazardous Substances Data)

Upstream product

• 107-10-8 propylamine 
• 6484-25-9 4-chloro-2-phenylquinazoline 
• 134-20-3 2-carbomethoxyaniline 
• 98-88-4 benzoyl chloride 
• 556-53-6 N-propylamine hydrochloride 
• 7510-49-8 methyl 2-(benzamido)benzoate 

Relevant articles and documents

QUINAZOLINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DIABETES AND OBESITY

The present invention relates to novel quinazoline derivatives effective in lowering blood glucose level and body weight, and a medicine for treatment and/or prevention of diabetes and/or obesity, which comprises the compound as an active ingredient.

Phosphoramides. XIII. Phosphorus Pentaoxide-Amine Hydrochloride Mixtures as Reagents in the Synthesis of 4(3H)-Quinazolinones and 4-Quinazolinamines

4(3H)-Quinazolinones 3a-r have been prepared by heating methyl N-acylanthranilates 1a-c and the hydrochlorides of primary aliphatic and aromatic amines with phosphorus pentaoxide and N,N-dimethylcyclohexylamine at 180 deg C. 4-Quinazolinamines 4 and the amidine 7 were isolated as by-products.The carboxamides 5 and 6 were believed to be reaction intermediates.By raising the temperature to 250 deg C 4 was obtained in a preparative yield.