77729-08-9

Upstream product

• 123-30-8 4-amino-phenol 
• 77725-90-7 4-(p-benzyloxyphenyl)aminoquinazoline 
• 5190-68-1 4-chloroquinazoline 
• 491-36-1 4-Hydroxyquinazoline 
• 50-00-0 formaldehyd 
• 34923-98-3 4-(p-hydroxyphenyl)aminoquinazoline 
• 109-89-7 diethylamine 
• 51387-92-9 4-amino-2-((diethylamino)methyl)phenol 
• 121-78-8 N-{3-[(diethylamino)methyl]-4-hydroxyphenyl}acetamide 
• 103-90-2 4-acetaminophenol 

Relevant academic research and scientific papers

Quinazoline derivative and preparation method and application thereof

The invention discloses a novel compound 4-(3 '-R substituted-5'-R substituted-4 '-hydroxyanilino) quinazoline derivative and a preparation method and application thereof. The structural formulas of the compound are shown as formulas I and II. The compound has good activity of preventing and treating chicken coccidiosis and can be used as a therapeutic agent for preventing and treating chicken coccidiosis in the field of preparation of medicines for preventing and treating chicken coccidiosis.

Studies in Potential Filaricides: Part XI - Synthesis of 2-Dialkylaminomethyl-4-substitutedamino-phenols as Amodiaquine Analogs

A number of 4,7-disubstituted quinazolines (11-17) and 2-dialkylaminomethyl-4-acetylaminophenols (19-30) have been synthesized and tested for their antifilarial activity against Litosomoides carinii in cotton rat (Sigmodon hispidus).Of the compounds tested 19-21 and 26 cause 60percent fall in microfilarial count at a dose of 30 mg/kg given intraperitoneally daily for 6 days.None of the compounds possesses any macrofilaricidal activity.