77756-31-1

Basic information

• Product Name: 2-(α-hydroxybenzyl)-3-thiophenecarboxylic acid
• Synonyms: 2-(α-hydroxybenzyl)-3-thiophenecarboxylic acid
• CAS NO: 77756-31-1
• Molecular Weight: 234.276
• Mol File: 77756-31-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(α-hydroxybenzyl)-3-thiophenecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(α-hydroxybenzyl)-3-thiophenecarboxylic acid(77756-31-1)
• EPA Substance Registry System: 2-(α-hydroxybenzyl)-3-thiophenecarboxylic acid(77756-31-1)

Safety Data

• Hazardous Substances Data: 77756-31-1(Hazardous Substances Data)

Upstream product

• 88-13-1 3-Thiophene carboxylic acid 
• 100-52-7 benzaldehyde 

Downstream Products

• 80727-84-0 7-phenylthieno[2,3-d]pyridazin-4(5H)-one 
• 1309195-34-3 5-amino-7-phenylthieno[2,3-d]pyridazin-4(5H)-one 
• 30011-75-7 2-(phenylcarbonyl)thiophene-3-carboxylic acid 
• 950911-21-4 6-phenyl-6H-thieno[2,3-c]furan-4-one 
• 86752-05-8 methyl 2-(α-hydroxybenzyl)thiophen-3-carboxylate 

Relevant articles and documents

Development of novel pyridazinone-based adenosine receptor ligands

With the aim of finding new adenosine receptor (AR) ligands, a preliminary investigation focusing on the thieno[2,3-d]pyridazin-5(4H)-one scaffold was undertaken. The synthesized compounds 1–11 were evaluated for their binding at hA1, hA2A

Generation and Synthetic Utility of Dianions Derived from Thiophencarboxylic Acids

Thiophen-2- and -3-carboxylic acid are rapidly and regioselectively metallated by lithium di-isopropylamide in tetrahydrofuran at -78 deg C.The resulting dianionic species react with a range of electrophiles to give the expected thiophencarboxylic acid homologues in good-to-excellent yields.