Development of novel pyridazinone-based adenosine receptor ligands

DOI: 10.1016/j.bmcl.2018.03.086

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1484 - 1489 (2018)

Update date:2022-08-04

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Authors:

Catarzi, Daniela

Varano, Flavia

Falsini, Matteo

Varani, Katia

Vincenzi, Fabrizio

Pasquini, Silvia

Dal Ben, Diego

Colotta, Vittoria

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Article abstract of DOI:10.1016/j.bmcl.2018.03.086

With the aim of finding new adenosine receptor (AR) ligands, a preliminary investigation focusing on the thieno[2,3-d]pyridazin-5(4H)-one scaffold was undertaken. The synthesized compounds 1–11 were evaluated for their binding at hA₁, hA_2A

Full text of DOI:10.1016/j.bmcl.2018.03.086

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