77862-72-7

Basic information

• Product Name: (5-Oxo-1,3-dioxolane-4,4-diyl)bis(acetic acid methyl) ester
• Synonyms: (5-Oxo-1,3-dioxolane-4,4-diyl)bis(acetic acid methyl) ester;5-Oxo-1,3-dioxolane-4,4-diacetic acid dimethyl ester
• CAS NO: 77862-72-7
• Molecular Weight: 0
• Mol File: 77862-72-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (5-Oxo-1,3-dioxolane-4,4-diyl)bis(acetic acid methyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: (5-Oxo-1,3-dioxolane-4,4-diyl)bis(acetic acid methyl) ester(77862-72-7)
• EPA Substance Registry System: (5-Oxo-1,3-dioxolane-4,4-diyl)bis(acetic acid methyl) ester(77862-72-7)

Safety Data

• Hazardous Substances Data: 77862-72-7(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 144-16-1 5-oxo-1,3-dioxolan-4-ylidenedi(acetic acid) 
• 50-00-0 formaldehyd 
• 53798-96-2 1,5-dimethyl citrate 
• 186581-53-3 diazomethane 

Downstream Products

• 77-93-0 citric acid triethyl ester 
• 199341-50-9 ((S)-4-Methoxycarbonylmethyl-5-oxo-[1,3]dioxolan-4-yl)-acetic acid 
• 199341-35-0 [(4R)-(+)-4-(2-methoxy-2-oxoethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid 
• 53798-96-2 1,5-dimethyl citrate 

Relevant articles and documents

Regio- and enantioselectivity of the enzyme-catalyzed hydrolysis of citric acid derivatives

The hydrolysis of triethyl citrate in the presence of three serine proteases (chymotrypsin, subtilisin BPN', subtilisin carlsberg) is highly regioselective and gives the symmetric diester. Several lipases and proteases have the complementary regioselectivity and give the chiral diester. Pig liver esterase, Aspergillus niger lipase and Candida antarctica lipase give the chiral (R)-diester with good regio- and enantioselectivity. The stereoselective hydrolysis of the meso citric derivatives 7a,b in the presence of Candida antarctica lipase gives the corresponding (R)-monoester.