77937-19-0Relevant academic research and scientific papers
LITHIATED DIHYDROPYRANS AS KETONE ENOLATE EQUIVALENTS: A MODEL STUDY FOR THE HERBICIDINS
Cox, Paul,Mahon, Mary F.,Molloy, Kieran C.,Lister, Simon,Gallagher, Timothy
, p. 1993 - 1996 (1988)
The synthesis of 6-lithio-5-methoxy-3,4-dihydro-2H-pyran (6) and its use as a regiospecific ketone enolate equivalent is described for the first time.This anion has been used to prepare the bicyclic hemiketal (5), a synthetic model for herbicidin B (1).
Regiospecific Enolates from Tetrahydropyran-3-one. Synthetic Equivalents of a Thermodynamically and Kinetically Disfavoured Enolate Isomer
Cox, Paul,Lister, Simon,Gallagher, Timothy
, p. 3151 - 3157 (2007/10/02)
Two synthetic equivalents of the tetrahydropyran-3-one enolate 3 are described.Lithiation of the methoxy enol ether 8b provides the β-lithiated enol ether 10 and although this species does serve as an equivalent of the enolate 3, its use is limited by the
