77973-25-2 Usage
Uses
Used in Pharmaceutical Synthesis:
1-(2-DIMETHYLAMINOMETHYL-4-METHOXY-PHENYL)-ETHANONE is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a versatile building block in the creation of different medicinal compounds, contributing to the development of new drugs and therapies.
Used in Organic Compound Production:
In the field of organic chemistry, 1-(2-DIMETHYLAMINOMETHYL-4-METHOXY-PHENYL)-ETHANONE is used as an intermediate for the production of a wide range of organic compounds. Its presence in these reactions enables the formation of complex molecules with potential applications in various industries, such as agriculture, materials science, and the chemical industry.
Used in Chemical Research:
As a reagent, 1-(2-DIMETHYLAMINOMETHYL-4-METHOXY-PHENYL)-ETHANONE is employed in chemical research to study the properties and reactions of various organic molecules. Its use in research helps scientists understand the behavior of similar compounds and develop new methods for synthesizing complex organic structures.
Check Digit Verification of cas no
The CAS Registry Mumber 77973-25-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,9,7 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 77973-25:
(7*7)+(6*7)+(5*9)+(4*7)+(3*3)+(2*2)+(1*5)=182
182 % 10 = 2
So 77973-25-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H17NO2/c1-9(14)12-6-5-11(15-4)7-10(12)8-13(2)3/h5-7H,8H2,1-4H3
77973-25-2Relevant academic research and scientific papers
Cationic chalcone antibiotics. Design, synthesis, and mechanism of action
Nielsen, Simon F.,Larsen, Mogens,Boesen, Thomas,Sch?nning, Kristian,Kromann, Hasse
, p. 2667 - 2677 (2007/10/03)
This paper describes how the introduction of "cationic" aliphatic amino groups in the chalcone scaffold results in potent antibacterial compounds. It is shown that the most favorable position for the aliphatic amino group is the 2-position of the B-ring, in particular in combination with a lipophilic substituent in the 5-position of the B-ring. We demonstrate that the compounds act by unselective disruption of cell membranes. Introduction of an additional aliphatic amino group in the á-ring results in compounds that are selective for bacterial membranes combined with a high antibacterial activity against both Gram-positive and -negative pathogens. The most potent compound in this study (78) has an MIC value of 2 μM against methicillin resistant Staphylococus aureus.
A NEW REGIOSPECIFIC SYNTHESIS OF ARYL KETONES FROM PALLADOCYCLES
Holton, R. A.,Natalie, K. J.
, p. 267 - 270 (2007/10/02)
Aromatic palladocycles undergo facile reaction with acid halides to regiospecifically provide aryl ketones in high yield.
