782-18-3

Usage

InChI:InChI=1/C14H11NO/c15-12-7-5-10(6-8-12)14-9-11-3-1-2-4-13(11)16-14/h1-9H,15H2

Upstream product

• 787-64-4 2-(4-nitrophenyl)-1-benzofurane 
• 98437-24-2 benzofuran-2-boronic acid 
• 106-40-1 4-bromo-aniline 
• 533-58-4 2-Iodophenol 
• 14235-81-5 4-Ethynylaniline 
• 90-02-8 salicylaldehyde 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 17490-72-1 2-(4-nitrobenzyloxy)benzaldehyde 
• 1104637-65-1 2-benzofuranylboronic acid mida ester 
• 540-37-4 p-aminoiodobenzene 

Downstream Products

• 101046-17-7 N-<4-(2-benzofuranyl)phenyl>maleamic acid 
• 1046317-48-9 4-[2-(4-benzofuran-2yl-phenylcarbamoyl)-2-(4-bromo-phenyl)-ethyl]-benzoic acid methyl ester 
• 1373220-83-7 C₁₇H₁₂N₂O 
• 1373220-98-4 Br^(1-)*C₂₅H₁₉N₂O₂⁽¹⁺⁾ 
• 1373221-00-1 Br^(1-)*C₂₅H₁₉N₂O₃⁽¹⁺⁾ 
• 1373221-02-3 Br^(1-)*C₂₆H₂₁N₂O₃⁽¹⁺⁾ 
• 1373221-04-5 Br^(1-)*C₂₅H₁₈FN₂O₂⁽¹⁺⁾ 
• 1373221-06-7 Br^(1-)*C₂₅H₁₈BrN₂O₂⁽¹⁺⁾ 
• 1373220-86-0 Br^(1-)*C₂₄H₁₉N₂O⁽¹⁺⁾ 
• 1373220-89-3 Br^(1-)*C₂₄H₁₈BrN₂O⁽¹⁺⁾ 
• 1373220-92-8 Br^(1-)*C₂₀H₁₇N₂O⁽¹⁺⁾ 
• 1373220-95-1 C₂₁H₂₁N₂O⁽¹⁺⁾*I^(1-) 

Relevant academic research and scientific papers

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Novel compound and organic light emitting device comprising the same

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NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME

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The invention belongs to the technical field of medicines, and discloses an autophagy inhibitor and application thereof. The general structural formula of the inhibitor is as shown in a formula I. Inthe formula I, R1 is monosubstituted; R2 is monosubstituted, disubstituted or polysubstituted; X is one selected from a group consisting of O, S, Se, NH, NR3, P(O)R3, CH2, CHR and CR3R4; and substituent groups R1, R2, R3 and R4 are independently selected from H, halogen, -CF3, -CN, -NO2, -OH, -NH2 and the like. The autophagy inhibitor can effectively inhibit the activity of ATG4B and inhibit the function of lysosome so as to block the process of cell autophagy, and can be used as a bifunctional autophagy inhibitor; and meanwhile, the autophagy inhibitor has good anti-tumor cell proliferation activity and can be used for preparing anti-tumor drugs.

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FLT3 inhibitors have been explored as a viable therapy for acute myeloid leukemia (AML). However, the clinical outcomes of these FLT3 inhibitors were underwhelming except AC220. Therefore, the development of novel FLT3 inhibitors with high potency against

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Abstract Palladium nanoparticles (PdNPs) were used as a catalyst for the one-pot synthesis of a variety of benzofurans by Sonogashira cross-coupling reactions under ambient conditions. The catalyst could be recycled without significant loss in its activity.

Transforming Suzuki-Miyaura cross-couplings of MIDA boronates into a green technology: No organic solvents

New technology has been developed that enables Suzuki-Miyaura couplings involving widely utilized MIDA boronates to be run in water as the only medium, mainly at room temperature. The protocol is such that no organic solvent is involved at any stage; from the reaction through to product isolation. Hence, using the E factor scale as a measure of greenness, the values for these cross-couplings approach zero.