78283-23-5

Basic information

• Product Name: 1H-Indole, 1-hydroxy-4-nitro-
• CAS NO: 78283-23-5
• Molecular Formula: C8H6N2O3
• Molecular Weight: 178.147
• Mol File: 78283-23-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 1-hydroxy-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 1-hydroxy-4-nitro-(78283-23-5)
• EPA Substance Registry System: 1H-Indole, 1-hydroxy-4-nitro-(78283-23-5)

Safety Data

• Hazardous Substances Data: 78283-23-5(Hazardous Substances Data)

Upstream product

• 78283-21-3 3-nitro-trans-2-[β-(dimethylamino)vinyl]-nitrobenzene 

Downstream Products

• 81038-38-2 4-iodo-1H-indole 
• 79133-59-8 4-(3-hydroxy-3-methyl-1-buten-1-yl)indole 
• 81038-34-8 1-(p-toluenesulphonyl)-4-hydroxyindole 
• 101909-45-9 4-bromo-1-methoxycarbonylindole 
• 81038-28-0 4-nitro-1-tosyl-1H-indole 
• 81038-31-5 1-tosyl-1H-indol-4-amine 
• 81038-29-1 1-benzyl-4-nitro-1H-indole 
• 81038-41-7 1-methoxycarbonyl-4-nitroindole 
• 81038-32-6 1-benzyl-1H-indol-4-ylamine 
• 81038-30-4 4-amino-1-methoxycarbonylindole 
• 40247-57-2 4-chloro-3-dimethylaminomethylindole 
• 30000-78-3 1-benzyl-4-(benzyloxy)-1H-indole 
• 27866-64-4 4-hydroxy-1-(phenylmethyl)-1H-indole 
• 16136-52-0 4-cyanoindole 

Relevant articles and documents

Some Observations on the Formation of 1-Hydroxyindoles in the Leimgruber-Batcho Indole Synthesis

The factors influencing the formation of 1-hydroxyindoles in the catalytic hydrogenation of β-dimethylamino-2-nitrostyrenes (Leimgruber-Batcho indole synthesis) have been investigated.Significant amounts of 1-hydroxyindoles were obtained only when the β-dimethylamino-2-nitrostyrene was substituted with an electron-withdrawing group at the 5 or 6 position.The proportion of 1-hydroxyindole formed relative to the normal indole product was found to increase as both the amount of catalyst and hydrogen pressure were decreased.