81038-34-8Relevant articles and documents
Design, synthesis and evaluation of dihydropyranoindole derivatives as potential cholinesterase inhibitors against Alzheimer's disease
Shaikh, Sarfaraz,Pavale, Ganesh,Dhavan, Pratik,Singh, Pinky,Uparkar, Jasmin,Vaidya,Jadhav,Ramana
, (2021)
A series of novel dihydropyranoindole derivatives containing sulphonamide group were designed, synthesized and evaluated for in-vitro anti-cholinesterase activity. The result showed that all the compounds exhibited potent acetylcholinesterase (AChE) activ
Application of E1cB Elimination in Asymmetric Organocatalytic Cascade Reactions to Construct Polyheterocyclic Compounds
You, Zhi-Hao,Chen, Ying-Han,Tang, Yu,Liu, Yan-Kai
supporting information, p. 8358 - 8363 (2019/10/16)
By introducing a carbon functionality at 2-position of chromane, the formal asymmetric functionalization of the 3-position of 2-substituted chromane has been realized via a highly chemo-, regio-, and stereoselective organocatalytic cascade reaction in a sequential one-pot manner involving an E1cB mechanism governed ring-opening process. Critical to our success was the design of a chiral dipeptide-based bifunctional acid-base organocatalyst, which exhibited high catalytic activity at low catalyst loading (1-0.1 mol %), leading to biologically interesting polyheterocyclic compounds.
Preparation of alkyl-substituted indoles in the benzene portion. Part 6. Synthetic procedure for 4-, 5-, 6-, or 7-alkoxy-and hydroxyindole derivatives
Fuji,Muratake,Natsume
, p. 2344 - 2352 (2007/10/02)
A novel method for the preparation of indole derivatives that are alkoxy- and hydroxy-substituted in the benzene portion of the indole nucleus is described. The acid-induced cyclization reaction of (arylsulfonyl)pyrrole derivatives (4a, 4b, 5b, and 5a) in