78329-40-5Relevant articles and documents
C-H alkenylations with alkenyl acetates, phosphates, carbonates, and carbamates by cobalt catalysis at 23 °C
Moselage, Marc,Sauermann, Nicolas,Richter, Sven C.,Ackermann, Lutz
, p. 6352 - 6355 (2015/05/20)
Inexpensive cobalt catalysts with N-heterocyclic carbene ligands enable direct arene alkenylations with easily accessible alkenyl acetates through regioselective C-H/C-O functionalizations in a stereoconvergent fashion. The versatile cobalt catalyst was b
Photochemistry of benzotriazoles: Generation of 1,3-diradicals and intermolecular cycloaddition as a new route toward indoles and dihydropyrrolo[3,4-b]indoles
Al-Jalal, Nader A.,Ibrahim, Maher R.,Al-Awadi, Nouria A.,Elnagdi, Mohamed H.,Ibrahim, Yehia A.
, p. 20695 - 20708 (2015/03/03)
Irradiation of benzotriazoles 1a-e at λ = 254 nm in acetonitrile solution generated the corresponding 1,3-diradicals which underwent intermolecular cycloaddition with maleimides to afford the corresponding dihydropyrrolo[3,4-b]indoles and with acetylene derivatives to afford indoles as the major products. This offers an interesting and simple access to such ring systems of potential synthetic and biological interest. The structures of the photoproducts were established spectroscopically and by single crystal X-ray crystallography.
An efficient new route towards biologically active isocryptolepine and γ-carboline derivatives using an intramolecular thermal electrocyclization strategy
Hingane, Dattatray G.,Kusurkar, Radhika S.
scheme or table, p. 3686 - 3688 (2011/07/31)
An efficient and short route is established for biologically active 11H-indolo[3,2-c]quinoline 1, naturally occurring antiplasmodial isocryptolepine 2 and 5-methyl-11H-indolo[3,2-c]quinoline-5-inium iodide 3 using intramolecular thermal electrocyclization
One-Pot synthesis of indoles and aniline derivatives from nitroarenes under hydrogenation condition with supported gold nanoparticles
Yamane, Yoshihiro,Liu, Xiaohao,Hamasaki, Akiyuki,Ishida, Tamao,Haruta, Masatake,Yokoyama, Takushi,Tokunaga, Makoto
supporting information; experimental part, p. 5162 - 5165 (2009/12/28)
One-pot sequences of hydrogenation/hydroamination to form indoles from (2-nitroaryl)alkynes and hydrogenation/reductive amination to form aniline derivatives from nitroarenes and aldehydes were catalyzed by Au nanoparticles supported on Fe2O3. Nitro group selective hydrogenations and successive reactions were efficiently catalyzed under the conditions.
Heterobimetallic cobalt/rhodium nanoparticle-catalyzed carbonylative cycloaddition of 2-alkynylanilines to oxindoles
Park, Ji Hoon,Kim, Eunha,Chung, Young Keun
supporting information; experimental part, p. 4718 - 4721 (2009/05/31)
(Chemical Equation Presented) The cobalt-rhodium heterobimetallic nanoparticle-catalyzed synthesis of oxindoles from 2-alkynylanilines in the presence of carbon monoxide is described.
Simple indole synthesis by one-pot sonogashira coupling-NaOH-mediated cyclization
Sanz, Roberto,Guilarte, Verónica,Castroviejo, M. Pilar
body text, p. 3006 - 3010 (2009/07/03)
Coupling of o-iodoanilines with terminal alkynes under standard Sonogashira conditions, and further treatment with NaOH under conventional heating or microwave irradiation, afford 2-substituted indoles in usually high yields. Functionalities such as halides, nitro, and cyano groups are tolerated under the reaction conditions. Georg Thieme Verlag Stuttgart.
Synthesis and structure-activity relationships of novel poly(ADP-ribose) polymerase-1 inhibitors
Tao, Ming,Park, Chung Ho,Bihovsky, Ron,Wells, Gregory J.,Husten, Jean,Ator, Mark A.,Hudkins, Robert L.
, p. 938 - 942 (2007/10/03)
A series of novel pyrrolocarbazoles was synthesized as potential PARP-1 inhibitors. Pyrrolocarbazole 1 was identified as a potent PARP-1 inhibitor (IC50 = 36 nM) from our internal database. Synthesis of analogs around this template with the aid
One-pot 2-aryl/vinylindole synthesis consisting of a ruthenium-catalyzed hydroamination and a palladium-catalyzed heck reaction using 2-chloroaniline
Ackermann, Lutz,Althammer, Andreas
, p. 3125 - 3129 (2008/02/13)
A one-pot synthesis of 2-aryl- and 2-vinylindoles based on a ruthenium-catalyzed hydroamination and a palladium-catalyzed intramolecular Heck reaction is reported. The ruthenium-catalyzed addition reaction was applied to terminal as well as internal alkynes. Intramolecular Heck reactions of the resulting 2-chloroanilino enamines were achieved using an in situ generated palladium complex derived from an N-heterocyclic carbene. Georg Thieme Verlag Stuttgart.
Synthesis of 2-substituted indoles by palladium-catalyzed heteroannulation with Pd-NaY zeolite catalysts
Hong, Ki Bum,Lee, Chul Wee,Yum, Eul Kgun
, p. 693 - 697 (2007/10/03)
Various 2-substituted indoles were prepared by heteroannulation of o-iodoanilines and terminal alkynes in a one-pot reaction with a Pd(II)-NaY zeolite catalyst. The product formation largely depended on the solvent, base, and reaction temperature. The recycled catalyst showed good reusability in the heteroannulation reaction.
Synthesis of polyfunctional indoles and related heterocycles mediated by cesium and potassium bases
Koradin, Christopher,Dohle, Wolfgang,Rodriguez, Alain L.,Schmid, Bertram,Knochel, Paul
, p. 1571 - 1587 (2007/10/03)
A general preparation of 2-substituted indoles starting from functionalized 2-alkynylanilines has been developed. This base mediated reaction has also been used to synthesize the heterocyclic core of the marine alkaloid hinckdentine A. Furthermore the reaction was successfully adapted to the solid phase. Benzofurans and isoindolones could also be prepared with this method.
