783345-23-3Relevant academic research and scientific papers
Enantioselective syntheses of bicyclo[3.1.0]hexane carboxylic acid derivatives by intramolecular cyclopropanation
Yoshikawa, Naoki,Tan, Lushi,Yasuda, Nobuyoshi,Volante, Ralph P.,Tillyer, Richard D.
, p. 7261 - 7264 (2007/10/03)
The title compounds serve as intermediates for the synthesis of mGluR agonists, which are useful for the treatment of CNS-related disorders. Enantioselective syntheses of bicyclo[3.1.0]hexane carboxylic acid derivatives are described. The syntheses were achieved by an intramolecular cyclopropanation as the key step, starting from enantiomerically pure starting materials that are commercially available.
