783357-49-3

Upstream product

• 75-64-9 tert-butylamine 
• 783357-48-2 3-(2-chloro-4-fluoro-5-nitrophenyl)-3-oxopropionic acid ethyl ester 
• 120890-66-6 2-chloro-4-fluoro-5-nitrobenzoyl chloride 
• 2252-51-9 2-choro-4-fluorobenzoic acid 

Relevant academic research and scientific papers

New 6-nitroquinolones: Synthesis and antimicrobial activities

Pursuing our searches on quinolonecarboxylic acids we used a simple three-step one pot procedure to synthesize novel 1,7-disubstituted-6- nitroquinolones. The new derivatives were tested against Mycobacterium tuberculosis and Mycobacterium avium complex (

Nitroquinolones with broad-spectrum antimycobacterial activity in vitro

During search on quinolonecarboxylic acids we used a facile, convenient two- or three-step procedure to synthesize new quinolone analogs, bearing at the C-7 position alkylamino substituents, and at the C-6 position a fluorine or alternatively a nitro grou