78570-35-1

Upstream product

• 1122-62-9 2-acetylpyridine 
• 78570-34-0 3,3-bis(methylsulfanyl)-1-pyridin-2-ylprop-2-en-1-one 
• 75-15-0 carbon disulfide 
• 74-88-4 methyl iodide 
• 81874-50-2 3-(methylsulfanyl)-1,5-di(pyridin-2-yl)pent-2-ene-1,5-dione 
• 128143-89-5 4'-Chloro-2,2':6',2''-terpyridine 
• 871232-96-1 [2,2′:6′,2″-terpyridine]-4′(1′H)-thione 

Downstream Products

• 108295-45-0 4′-formyl-2,2′:6′2″-terpyridine 
• 1148-79-4 2,2':6,2''-terpyridine 
• 145533-40-0 4'-ethoxy-2,2' : 6',2''-terpyridine 
• 81874-51-3 4'-(methylsulfonyl)-2,2':6',2''-terpyridine 
• 72036-41-0 4'-methyl-2,2':6',2''-terpyridine 

Relevant academic research and scientific papers

A General Scheme For Incorporating Nonnatural Functionality Into Peptides

We describe a convergent synthesis of ΔGCN4229-248-terpyridyl 1, which contains a terpyridyl ligand attached covalently through a disulfide bond to the proposed DNA binding domain of the yeast transcriptional activator protein GCN4

New Approaches to the Synthesis of 2,2′: 6′,2″-Terpyridine and Some of Its Derivatives

A new two-step procedure has been developed for the synthesis of 2,2′: 6′,2″-terpyridine and 4′-methylsulfanyl-2,2′: 6′,2″-terpyridine in more than 70% yield on the basis of Potts’ condensation. Efficient methods have been proposed for purification of all condensation products.

One-pot synthesis of an Fe(II) bis-terpyridine complex with allosterically regulated electronic properties

Herein we report the one-pot synthesis of Fe(II) bis-terpyridine complexes with two peripheral square-planar Pt(II) bis-phosphinoalkylthioether moieties. These novel structures, which exhibit allosterically controllable electronic properties, are made by

4-Vinyl-, 6-Vinyl-, and 4'-Vinyl-2,2':6',2''-terpyridinyl Ligands: Their Synthesis and the Electrochemistry of Their Transition-Metal Coordination Complexes

4'-Vinyl-2,2':6',2''-terpyridinyl was conveniently prepared from 2-acetylpyridine via α-oxoketene dithioacetal methodology, the intermediate 4'-(methylthio)-2,2':6',2''-terpyridinyl being converted into the corresponding 4'-methyl derivative with methylma

Synthesis of 2,6-Disubstituted Pyridines, Polypyridinyls, and Annulated Pyridines

1,5-Enediones containing a variety of substituents in the 1,5-positions are formed in good yields by the reaction of methyl ketone enolates, generated with potassium tert-butoxide, with α-oxoketene dithioacetals, the latter being prepared from alkyl, cycloalkyl, aryl, or heteryl methyl ketones, NaH, CS2, and CH3I.Ring closure of the 1,5-enediones with NH4OAc gave 2,6-disubstituted 4-(methylthio)pyridines in good to excellent yields.This procedure is particularly suited for the synthesis of 2,6-diheterylpyridines and provides a simple synthesis of terpyridinyl and other oligopyridines.The methylthio groups in the α-oxoketene dithioacetals may be oxidized to the mono- and disulfoxides with m-chloroperbenzoic acid, but with excess peracid, in addition to oxidation to the disulfone, epoxidation of the double bond also occurs.The pyridine 4-methylthio substituent may also be oxidized to the sulfoxide and to the sulfone, and the latter may be displaced with cyanide ion to form the corresponding 4-carbonitrile.