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Fluvastatin Methyl Ester is a chemical compound derived from fluvastatin, a medication used to treat high cholesterol and prevent cardiovascular disease. It is an ester form of fluvastatin that is more lipophilic, meaning it has a greater ability to dissolve in fat. This property allows for better absorption and distribution in the body, ultimately leading to increased efficacy of the medication.
Used in Pharmaceutical Industry:
Fluvastatin Methyl Ester is used as a pharmaceutical formulation for improving the bioavailability and therapeutic effect of fluvastatin. Its enhanced lipophilicity allows for better absorption and distribution in the body, making it a valuable tool in the treatment of hypercholesterolemia and related conditions.

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  • 786710-21-2 Structure
  • Basic information

    1. Product Name: Fluvastatin Methyl Ester
    2. Synonyms: methyl [3R,5S-(E)]-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoate;6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, methyl ester, (3R,5S,6E)-
    3. CAS NO:786710-21-2
    4. Molecular Formula: C25H28FNO4
    5. Molecular Weight: 425.4925232
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 786710-21-2.mol
    9. Article Data: 4
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 627.5±55.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.18±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 13.54±0.20(Predicted)
    10. CAS DataBase Reference: Fluvastatin Methyl Ester(CAS DataBase Reference)
    11. NIST Chemistry Reference: Fluvastatin Methyl Ester(786710-21-2)
    12. EPA Substance Registry System: Fluvastatin Methyl Ester(786710-21-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 786710-21-2(Hazardous Substances Data)

786710-21-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 786710-21-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,8,6,7,1 and 0 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 786710-21:
(8*7)+(7*8)+(6*6)+(5*7)+(4*1)+(3*0)+(2*2)+(1*1)=192
192 % 10 = 2
So 786710-21-2 is a valid CAS Registry Number.

786710-21-2Downstream Products

786710-21-2Relevant articles and documents

PROCESS FOR PREPARATING ENANTIOMERICALLY PURE FLUVASTATIN SODIUM AND A NOVEL POLYMORPHIC FORM THEREOF

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Page/Page column 21-22, (2008/06/13)

The present invention provides processes for preparing enantiomerically pure fluvastatin sodium. The present invention also provides pharmaceutical compositions comprising the enantiomerically pure fluvastatin sodium for antagonizing HMG-CoA. In addition

Method of separating optically active dihydroxy-heptenoic acid esters

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Page/Page column 8; 9; 10; 11, (2008/06/13)

An optically active dihydroxyheptenoic acid ester having an aromatic group is separated from a solution containing a mixture of optical isomers of digydroxyheptenoic acid ester by liquid chromatography with a packing material constituted of a carrier and

PROCESS AND INTERMEDIATES FOR THE SELECTIVE SYNTHESIS OF FLUVASTATIN

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Page/Page column 10, (2010/10/20)

The invention relates to process for the selective preparation of 3-hydroxy-6-dialkoxyphosphoryl-5-oxo-hexanoic acid esters, comprising a first step, in which a methylphosphonic acid dialkylester is treated with a base, and a second step, in which the pro

A Novel Method for the In Situ Generation of Alkoxydialkylboranes and Their Use in the Selective Preparation of 1,3-Syn Diols

Chen, Kau-Ming,Gunderson, Karl G.,Hardtmann, Goetz E.,Prasad, Kapa,Repic, Oljan,Shapiro, Michael J.

, p. 1923 - 1926 (2007/10/02)

An in situ method for generating Et2BOCH3 from triethylborane and methanol without using any other catalysts is described.Using the Et2BOCH3 thus generated as a chelating agent, syn 1,3-diols are prepared in > 98 percent stereochemical purity by reducing β-hydroxy-ketones with sodium borohydride

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