202479-37-6 Usage
Description
rac-Fluvastatin Methyl Ester (Mixture of diastereoMers) is a racemic analogue of Fluvastatin Methyl Ester (F601275), which is an intermediate compound used in the selective synthesis of Fluvastatin (F601250). This mixture consists of equal parts of two diastereomeric forms, which are non-superimposable mirror images of each other. The presence of these diastereomers in the mixture contributes to the overall properties and potential applications of rac-Fluvastatin Methyl Ester.
Uses
Used in Pharmaceutical Industry:
rac-Fluvastatin Methyl Ester (Mixture of diastereoMers) is used as an intermediate in the synthesis of Fluvastatin (F601250) for its cholesterol-lowering properties. Fluvastatin is a medication belonging to the class of statins, which are HMG-CoA reductase inhibitors. These inhibitors play a crucial role in reducing the levels of low-density lipoprotein (LDL) cholesterol in the blood, thus helping to prevent cardiovascular diseases.
Additionally, rac-Fluvastatin Methyl Ester (Mixture of diastereoMers) may also be utilized in research and development for the exploration of new pharmaceutical applications, given its unique diastereomeric composition. This could potentially lead to the discovery of novel therapeutic agents with improved efficacy and reduced side effects, further benefiting the pharmaceutical industry and patients alike.
Check Digit Verification of cas no
The CAS Registry Mumber 202479-37-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,2,4,7 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 202479-37:
(8*2)+(7*0)+(6*2)+(5*4)+(4*7)+(3*9)+(2*3)+(1*7)=116
116 % 10 = 6
So 202479-37-6 is a valid CAS Registry Number.
202479-37-6Relevant articles and documents
PROCESS FOR PREPARATING ENANTIOMERICALLY PURE FLUVASTATIN SODIUM AND A NOVEL POLYMORPHIC FORM THEREOF
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Page/Page column 21-22, (2008/06/13)
The present invention provides processes for preparing enantiomerically pure fluvastatin sodium. The present invention also provides pharmaceutical compositions comprising the enantiomerically pure fluvastatin sodium for antagonizing HMG-CoA. In addition
Method of separating optically active dihydroxy-heptenoic acid esters
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Page/Page column 7, (2008/06/13)
An optically active dihydroxyheptenoic acid ester having an aromatic group is separated from a solution containing a mixture of optical isomers of digydroxyheptenoic acid ester by liquid chromatography with a packing material constituted of a carrier and
A Novel Method for the In Situ Generation of Alkoxydialkylboranes and Their Use in the Selective Preparation of 1,3-Syn Diols
Chen, Kau-Ming,Gunderson, Karl G.,Hardtmann, Goetz E.,Prasad, Kapa,Repic, Oljan,Shapiro, Michael J.
, p. 1923 - 1926 (2007/10/02)
An in situ method for generating Et2BOCH3 from triethylborane and methanol without using any other catalysts is described.Using the Et2BOCH3 thus generated as a chelating agent, syn 1,3-diols are prepared in > 98 percent stereochemical purity by reducing β-hydroxy-ketones with sodium borohydride
