78794-55-5Relevant academic research and scientific papers
Synthesis, molecular docking study, and cytotoxic activity of 1,3,5-triaryl pyrazole derivatives
Ghasemi, Maryam,Ghadbeighi, Sajad,Amirhamzeh, Amirali,Tabatabai, Seyed Abbas,Ostad, Seyed Nasser,Shafiee, Abbas,Amini, Mohsen
, p. 121 - 128 (2016/03/12)
Synthesis, molecular docking study, and cytotoxic activity of a new group of 1,3,5-triaryl pyrazole derivatives were be studied. The antiproliferative activity of the final compounds were examined in MCF-7, AGS, HT-29 and NIH3T3 cell lines by MTT assay, u
Copper-catalyzed aerobic C(sp2)-H functionalization for C-N bond formation: Synthesis of pyrazoles and indazoles
Li, Xianwei,He, Li,Chen, Huoji,Wu, Wanqing,Jiang, Huanfeng
, p. 3636 - 3646 (2013/06/04)
A simple, practical, and highly efficient synthesis of pyrazoles and indazoles via copper-catalyzed direct aerobic oxidative C(sp2)-H amination has been reported herein. This process tolerated a variety of functional groups under mild conditions. Further diversification of pyrazoles was also investigated, which provided its potential for drug discovery.
Synthesis of tri- and tetrasubstituted pyrazoles via Ru(II) catalysis: Intramolecular aerobic oxidative C-N coupling
Hu, Jiantao,Chen, Shi,Sun, Yonghui,Yang, Jing,Rao, Yu
supporting information, p. 5030 - 5033,4 (2012/12/12)
An unprecedented ruthenium(II)-catalyzed intramolecular oxidative C-N coupling method has been developed for the facile synthesis of a variety of synthetically challenging tri- and tetrasubstituted pyrazoles. Dioxygen gas is employed as the oxidant in this transformation. The reaction demonstrates excellent reactivity, functional group tolerance, and high yields.
