78817-45-5Relevant academic research and scientific papers
A new 'one-pot' synthesis of hydrazides by reduction of hydrazones
Perdicchia, Dario,Licandro, Emanuela,Maiorana, Stefano,Baldoli, Clara,Giannini, Clelia
, p. 7733 - 7742 (2007/10/03)
A new, high-yielding methodology for reducing hydrazones to hydrazines is described, which allows the synthesis of different mono-, di- and trisubstituted hydrazines. Moreover, the reduction step can be followed by an in situ reaction with a carboxylic acid making possible a 'one-pot' synthesis of trisubstituted hydrazides. The method is relatively general and, in principle, suitable for industrial applications.
Amidrazones. VII (1a). Formation of s-Triazines by Thermolysis of N1-Benzyl-Substituted Amidrazone Ylides
Smith, Richard F.,Soelch, Richard R.,Feltz, Timothy P.,Martinelli, Michael J.,Geer, Susan M.
, p. 319 - 325 (2007/10/02)
The preparation of ylides of the general structure RC(=NR')N-N+(CH3)2CH2Ar (14) is described.Thermolysis of 14a (R = CH3, R' = H, Ar = C6H5) gave dimethylamine and 2,4-dimethyl-6-phenyl-s-triazine.Thermolysis of ylides 14b (R = C6H5; R' = CH3, Ar = C6H5) and 14c (R = C6H5, R' = CH3, Ar = p-tolyl) gave dimethylamine, ArCH=NCH3 and 1-methyl-2-Ar-4,6-diphenyl-1,2-dihydro-s-triazines (19a,b).Triazines 19a and 19b were also prepared by condensation of N-methylbenzamidine with benzaldehyde and p-tolualdehyde, respectively.Thermolysis of 14d (R = C6H5, R' = CH2C6H5, Ar = C6H5) gave 1-benzyl-2,4,6-triphenyl-1,2-dihydro-s-triazine (19c) and N-benzylidenebenzylamine.Mechanistic aspects of these reactions are discussed.
