79090-90-7Relevant academic research and scientific papers
REGIOSELECTIVITE DE LA REACTION DES DIALKYL CUPRATES DE MAGNESIUM SUR DES ALDEHYDES α,β-ETHYLENIQUES
Bourgain-Commercon, Monique,Foulon, Jean-Pierre,Normant, Jean Francois
, p. 321 - 326 (1982)
Various magnesium organocuprates give conjugative addition products with α,β-ethylenic aldehydes, and even with acrolein.The enolates may be trapped with bromine or trimethylsilyl chloride.
REACTIVITE DES DERIVES ORGANOCUIVREUX VIS-A-VIS DES ALDEHYDES αβ-ETHYLENIQUES
Chuit, C.,Foulon, J. P.,Normant, J. F.
, p. 1385 - 1389 (2007/10/02)
Secondary lithium dialkylcuprates react with αβ-ethylenic aldehydes to give a mixture of 1,2 and 1,4 addition products.Only 1,2 addition products are obtained with allylic and acetylenic cuprates whereas homallylic, phenyl and vinylic cuprates give 1,4 addition products.The 1,4/1,2 ratio also depends on the nature of the metal in the cuprate (Mg or Li).Thus chloromagnesium dimethyl cuprate, in THF, is the most favorable compound to give the 1,4 addition product.
