79114-07-1Relevant articles and documents
Biological evaluation in vitro and in silico of azetidin-2-one derivatives as potential anticancer agents
Olazaran, Fabián E.,Rivera, Gildardo,Pérez-Vázquez, Alondra M.,Morales-Reyes, Cynthia M.,Segura-Cabrera, Aldo,Balderas-Rentería, Isaías
supporting information, p. 32 - 37 (2017/12/13)
Potential anticancer activity of 16 azetidin-2-one derivatives was evaluated showing that compound 6 [N-(p-methoxy-phenyl)-2-(p-methyl-phenyl)-3-phenoxy-azetidin-2-one] presented cytotoxic activity in SiHa cells and B16F10 cells. The caspase-3 assay in B1
Preparation of 2-azetidinones by cyclocondensation of carboxylic acids and imines via diphosphorustetraiodide
Zarei, Maaroof,Maaqooli, Fatemeh
supporting information, p. 523 - 527 (2016/05/02)
One-pot mild synthesis of 2-azetidinones was carried out by the reaction of imines and carboxylic acids in dry dichloromethane at room temperature using diphosphorus tetraiodide. It was also applied for synthesis of 3-spiro-2-azetidinones. The synthesized
Solvent-free, one-pot synthesis of β-lactams by the Sc(OTf) 3-catalyzed reaction of silyl ketene thiocetals with imines
Benaglia, Maurizio,Cozzi, Franco,Puglisi, Alessandra
, p. 2865 - 2869 (2008/03/13)
A solvent-free, catalytic, one-pot synthesis of β-lactams is described. The reaction involves the reaction between silyl ketene thioacetals derived from 2-pyridyl thioesters and imines at room temperature in the presence of catalytic amounts of Sc(OTf)su
